Last Updated: September 28 2022

Eriobotrya japonica (Common Loquat) is a plant whose fruits are commonly consumed for their taste and other parts (seeds, leaves, flowers) used in traditional chinese medicine for treatment of cough and respiratory distress; it appears to be rich in ursolic acid like triterpenoids.

Loquat is most often used for


Eriobotrya japonica is the plant which bears the fruits we refer to as 'Loquat', or specifically the common or wild Loquat. While the fruits themselves are sold as a food product with no medicinal history, the seeds have been added to alcoholic drinks which are thought to promote longevity while the leaves have been ingested on an as-needed basis to treat cough, sputum, and throat inflammation associated with sickness.

The leaves themselves are a good source of triterpenoid molecules, with some unique ones including tormentic acid (and some variants) and euscaphic acid although the majority of these triterpenoids are just ursolic acid and a variety of methoxylated or polyhydroxylated variants. It seems to have a wider variety of triterpenoids rather than a high level of any one triterpenoid, and this class of molecules seems to underlie most of the benefits associated with the leaf extracts. There is not a good idea of what molecules are in the seeds, and it is though that they are also a source of triterpenoids since no unique molecules are known in them.

The benefits of this plant right now tend to be associated with either high or undisclosed doses of the seeds, suggesting that they probably don't apply to oral ingestion of standard doses in humans. The only roles where supplementation may be useful are in control of diabetes and possibly in reducing ulcer formation, but both of these claims can be achieved if not easily outperformed by using isolated ursolic acid or other supplements. There is not enough research into the variety of triterpenoid variations (the polyhydroxylated or methyoxylated variants) to know if they possess unique properties or not.

What else is Loquat known as?
Note that Loquat is also known as:
  • Loquat
  • Biwa
  • Pipa
  • Pipaye
  • Chinese Plum
  • Japanese Plum
  • Eriobotrya Japonica
Loquat should not be confused with:
Dosage information

There is currently not enough information to recommend an ideal supplemental dose of this plant for any of its recommended supplemental purposes, although one study referencing the 'recommended human dose' for the seeds used a rat dose of 40mg/kg (ie. abouto 3-5g of the seeds for adults).

Join our supplement information course

Enter your email to get a FREE five-day course on supplements. 100% backed by science, we take an independent and unbiased approach to figure out what works (and what's a waste of time and money).

    The only 100% independent company. While everyone sells supplements, we only analyze research.

    Don't miss out on the latest research

    Enter your email and we'll keep you on top of the latest nutrition research, supplement myths, and more

      1.^Ding CK, Chachin K, Ueda Y, Imahori Y, Wang CYMetabolism of phenolic compounds during loquat fruit developmentJ Agric Food Chem.(2001 Jun)
      15.^Banno N, Akihisa T, Tokuda H, Yasukawa K, Taguchi Y, Akazawa H, Ukiya M, Kimura Y, Suzuki T, Nishino HAnti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of Eriobotrya japonicaBiol Pharm Bull.(2005 Oct)
      16.^Ito H, Kobayashi E, Li SH, Hatano T, Sugita D, Kubo N, Shimura S, Itoh Y, Yoshida TMegastigmane glycosides and an acylated triterpenoid from Eriobotrya japonicaJ Nat Prod.(2001 Jun)
      18.^Taniguchi S, Imayoshi Y, Kobayashi E, Takamatsu Y, Ito H, Hatano T, Sakagami H, Tokuda H, Nishino H, Sugita D, Shimura S, Yoshida TProduction of bioactive triterpenes by Eriobotrya japonica calliPhytochemistry.(2002 Feb)
      19.^De Tommasi N, De Simone F, Pizza C, Mahmood N, Moore PS, Conti C, Orsi N, Stein MLConstituents of Eriobotrya japonica. A study of their antiviral propertiesJ Nat Prod.(1992 Aug)
      20.^Lee MH, Son YK, Han YNTissue factor inhibitory sesquiterpene glycoside from Eriobotrya japonicaArch Pharm Res.(2004 Jun)
      22.^Ito H, Kobayashi E, Li SH, Hatano T, Sugita D, Kubo N, Shimura S, Itoh Y, Tokuda H, Nishino H, Yoshida TAntitumor activity of compounds isolated from leaves of Eriobotrya japonicaJ Agric Food Chem.(2002 Apr 10)
      23.^Ito H, Kobayashi E, Takamatsu Y, Li SH, Hatano T, Sakagami H, Kusama K, Satoh K, Sugita D, Shimura S, Itoh Y, Yoshida TPolyphenols from Eriobotrya japonica and their cytotoxicity against human oral tumor cell linesChem Pharm Bull (Tokyo).(2000 May)
      24.^Jung HA, Park JC, Chung HY, Kim J, Choi JSAntioxidant flavonoids and chlorogenic acid from the leaves of Eriobotrya japonicaArch Pharm Res.(1999 Apr)
      25.^Pfisterer PH, Shen C, Nikolovska-Coleska Z, Schyschka L, Schuster D, Rudy A, Wolber G, Vollmar AM, Rollinger JM, Stuppner HIn silico discovery of acylated flavonol monorhamnosides from Eriobotrya japonica as natural, small-molecular weight inhibitors of XIAP BIR3Bioorg Med Chem.(2011 Jan 15)
      26.^Kawahara N, Satake M, Goda YA new acylated flavonol glycoside from the leaves of Eriobotrya japonicaChem Pharm Bull (Tokyo).(2002 Dec)
      27.^Kwon HJ, Kang MJ, Kim HJ, Choi JS, Paik KJ, Chung HYInhibition of NFkappaB by methyl chlorogenate from Eriobotrya japonicaMol Cells.(2000 Jun 30)
      28.^Song FL, Gan RY, Zhang Y, Xiao Q, Kuang L, Li HBTotal phenolic contents and antioxidant capacities of selected chinese medicinal plantsInt J Mol Sci.(2010 Jun 1)
      29.^Zhou C, Chen K, Sun C, Chen Q, Zhang W, Li XDetermination of oleanolic acid, ursolic acid and amygdalin in the flower of Eriobotrya japonica Lindl. by HPLCBiomed Chromatogr.(2007 Jul)
      30.^Cheng L, Liu Y, Chen L, Luo JStudies on the triterpenoidal saponins from flowers of Eriobotrya japonicaHua Xi Yi Ke Da Xue Xue Bao.(2001 Jun)
      31.^Tanaka K, Nishizono S, Makino N, Tamaru S, Terai O, Ikeda IHypoglycemic activity of Eriobotrya japonica seeds in type 2 diabetic rats and miceBiosci Biotechnol Biochem.(2008 Mar)
      32.^Li S, Zou Y, Jiao K, Qiao X, Jiao R, Wang JRepeated-dose (28 days) oral toxicity study in rats of an antiacne formula (BC-AF) derived from plantsDrug Chem Toxicol.(2011 Jan)
      34.^Toshima A, Matsui T, Noguchi M, Qiu J, Tamaya K, Miyata Y, Tanaka T, Tanaka KIdentification of alpha-glucosidase inhibitors from a new fermented tea obtained by tea-rolling processing of loquat (Eriobotrya japonica) and green tea leavesJ Sci Food Agric.(2010 Jul)
      40.^Muramoto K, Quan RD, Namba T, Kyotani S, Miyamura M, Nishioka Y, Tonosaki K, Doi YL, Kaba HAmeliorative effects of Eriobotrya japonica seed extract on cellular aging in cultured rat fibroblastsJ Nat Med.(2011 Apr)
      41.^Kim MJ, Lee J, Seong AR, Lee YH, Kim YJ, Baek HY, Kim YJ, Jun WJ, Yoon HGNeuroprotective effects of Eriobotrya japonica against β-amyloid-induced oxidative stress and memory impairmentFood Chem Toxicol.(2011 Apr)
      43.^Kotowaroo MI, Mahomoodally MF, Gurib-Fakim A, Subratty AHScreening of traditional antidiabetic medicinal plants of Mauritius for possible alpha-amylase inhibitory effects in vitroPhytother Res.(2006 Mar)
      44.^Qa'dan F, Verspohl EJ, Nahrstedt A, Petereit F, Matalka KZCinchonain Ib isolated from Eriobotrya japonica induces insulin secretion in vitro and in vivoJ Ethnopharmacol.(2009 Jul 15)
      45.^Lü H, Chen J, Li WL, Ren BR, Wu JL, Kang HY, Zhang HQ, Adams A, De Kimpe NHypoglycemic and hypolipidemic effects of the total triterpene acid fraction from Folium EriobotryaeJ Ethnopharmacol.(2009 Apr 21)
      46.^Lü H, Chen J, Li WL, Ren BR, Wu JL, Zhang HQHypoglycemic effect of the total flavonoid fraction from folium EriobotryaePhytomedicine.(2009 Oct)
      48.^Chen J, Li WL, Wu JL, Ren BR, Zhang HQEuscaphic acid, a new hypoglycemic natural product from Folium EriobotryaePharmazie.(2008 Oct)
      56.^Kim SH, Kwon YE, Park WH, Jeon H, Shin TYEffect of leaves of Eriobotrya japonica on anaphylactic allergic reaction and production of tumor necrosis factor-alphaImmunopharmacol Immunotoxicol.(2009 Jun)
      57.^Yokota J, Takuma D, Hamada A, Onogawa M, Yoshioka S, Kusunose M, Miyamura M, Kyotani S, Nishioka YGastroprotective activity of Eriobotrya japonica seed extract on experimentally induced gastric lesions in ratsJ Nat Med.(2008 Jan)
      58.^Sun G, Zhang Y, Takuma D, Onogawa M, Yokota J, Hamada A, Yoshioka S, Kusunose M, Miyamura M, Kyotani S, Nishioka YEffect of orally administered Eriobotrya japonica seed extract on allergic contact dermatitis in ratsJ Pharm Pharmacol.(2007 Oct)
      59.^Kang SC, Lee CM, Choi H, Lee JH, Oh JS, Kwak JH, Zee OPEvaluation of oriental medicinal herbs for estrogenic and antiproliferative activitiesPhytother Res.(2006 Nov)
      60.^Gumy C, Thurnbichler C, Aubry EM, Balazs Z, Pfisterer P, Baumgartner L, Stuppner H, Odermatt A, Rollinger JMInhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicinesFitoterapia.(2009 Apr)
      61.^Yokota J, Kitaoka T, Jobu K, Takuma D, Hamada A, Onogawa M, Yoshioka S, Kyotani S, Miyamura MEriobotrya japonica seed extract and deep sea water protect against indomethacin-induced gastric mucosal injury in ratsJ Nat Med.(2011 Jan)
      62.^Yokota J, Takuma D, Hamada A, Onogawa M, Yoshioka S, Kusunose M, Miyamura M, Kyotani S, Nishioka YScavenging of reactive oxygen species by Eriobotrya japonica seed extractBiol Pharm Bull.(2006 Mar)
      63.^Nishioka Y, Yoshioka S, Kusunose M, Cui T, Hamada A, Ono M, Miyamura M, Kyotani SEffects of extract derived from Eriobotrya japonica on liver function improvement in ratsBiol Pharm Bull.(2002 Aug)
      64.^Yoshioka S, Hamada A, Jobu K, Yokota J, Onogawa M, Kyotani S, Miyamura M, Saibara T, Onishi S, Nishioka YEffects of Eriobotrya japonica seed extract on oxidative stress in rats with non-alcoholic steatohepatitisJ Pharm Pharmacol.(2010 Feb)
      65.^Huang Y, Li J, Cao Q, Yu SC, Lv XW, Jin Y, Zhang L, Zou YH, Ge JFAnti-oxidative effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf in chronic bronchitis ratsLife Sci.(2006 May 1)
      69.^Hamada A, Yoshioka S, Takuma D, Yokota J, Cui T, Kusunose M, Miyamura M, Kyotani S, Nishioka YThe effect of Eriobotrya japonica seed extract on oxidative stress in adriamycin-induced nephropathy in ratsBiol Pharm Bull.(2004 Dec)
      70.^Liu Z, Sun C, Olejniczak ET, Meadows RP, Betz SF, Oost T, Herrmann J, Wu JC, Fesik SWStructural basis for binding of Smac/DIABLO to the XIAP BIR3 domainNature.(2000 Dec 21-28)
      71.^Wu G, Chai J, Suber TL, Wu JW, Du C, Wang X, Shi YStructural basis of IAP recognition by Smac/DIABLONature.(2000 Dec 21-28)
      74.^Kikuchi T, Akazawa H, Tabata K, Manosroi A, Manosroi J, Suzuki T, Akihisa T3-O-(E)-p-coumaroyl tormentic acid from Eriobotrya japonica leaves induces caspase-dependent apoptotic cell death in human leukemia cell lineChem Pharm Bull (Tokyo).(2011)
      75.^Cha DS, Shin TY, Eun JS, Kim DK, Jeon HAnti-metastatic properties of the leaves of Eriobotrya japonicaArch Pharm Res.(2011 Mar)
      76.^Kim MS, You MK, Rhuy DY, Kim YJ, Baek HY, Kim HALoquat (Eriobotrya japonica) extracts suppress the adhesion, migration and invasion of human breast cancer cell lineNutr Res Pract.(2009 Winter)
      77.^Uto T, Sakamoto A, Tung NH, Fujiki T, Kishihara K, Oiso S, Kariyazono H, Morinaga O, Shoyama YAnti-Proliferative Activities and Apoptosis Induction by Triterpenes Derived from Eriobotrya japonica in Human Leukemia Cell LinesInt J Mol Sci.(2013 Feb 18)
      78.^Takuma D, Guangchen S, Yokota J, Hamada A, Onogawa M, Yoshioka S, Kusunose M, Miyamura M, Kyotani S, Nishioka YEffect of Eriobotrya japonica seed extract on 5-fluorouracil-induced mucositis in hamstersBiol Pharm Bull.(2008 Feb)
      79.^Li WL, Wu JL, Ren BR, Chen J, Lu CGPharmacological studies on anti-hyperglycemic effect of folium eriobotryaeAm J Chin Med.(2007)