Quick Navigation

Hordenine

Hordenine (N,N-dimethyltyramine) is an adrenergic-like compound found in a variety of foods investigated for its fat-burning effects. May be a noradrenaline reuptake inhibitor.

Our evidence-based analysis on hordenine features 18 unique references to scientific papers.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Summary of Hordenine

Primary information, health benefits, side effects, usage, and other important details

Hordenine is a molecule found in a variety of plants alongside other adrenergic amines such as tyramine or synephrine, and has been linked to having adrenergic effects after intravenous administration. Practically, Hordenine is very underresearched and comparative analysis' between other stimulants cannot be conducted right now.

Technically Hordenine can be used as a stimulant and fat burner due to its associated with tyramine and noradrenaline, but not enough evidence exists currently to support its usage as nutritional supplementation.

Hordenine is on the FDA's Dietary Supplement Ingredient Advisory List as of April, 2019. These are ingredients that do not appear to be lawful ingredients in dietary supplements. The list is subject to change (check the provided link for current status).

Get trusted answers to health questions that matter to you

Getting an Examine.com subscription makes it easy for you to stay informed and understand the latest nutrition research.

If you’re overwhelmed by all the possibilities of supplementation and want step-by-step instructions on what supplements to take (how much, when, and in what combinations), then the Examine.com Supplement Guides are perfect for you.

Your support keeps us 100% independent, so that we never have a conflict of interest.


How to Take

Medical Disclaimer

Recommended dosage, active amounts, other details

There is currently insufficient evidence to recommend an oral dose of hordenine supplementation for human consumption.

Things to Note

Is a Form Of

Primary Function:

Also Known As

N, N-dimethyltyramine

Do Not Confuse With

Tyramine, Candicine, L-Tyrosine

Caution Notice

Hordenine may cause a false positive for opiate drugs in urine testing

  • Most likely stimulatory following high dose oral consumption

Get our free 5-day course on the essentials of supplementation.

At Examine.com, our incentives line up with yours — getting unbiased information. That's why we don’t sell any advertising or supplements.

Join over 250,000 people who have learned about effective versus overrated supplements, tips for buying supplements, and how to combine supplements for safety and efficacy.

Click here to see all 18 references.