Quick Navigation

Apigenin

One of the bioflavonoids, apigenin appears to be catered towards reducing anxiety and causing sedation. Found in chamomile tea, alcoholic beverages, and Bacopa Monnieri, apigenin is unstable by itself yet stable when consumed via foods and herbs.

Our evidence-based analysis on apigenin features 44 unique references to scientific papers.

Kamal Patel
Research analysis led by and reviewed by the Examine team.
Last Updated:

Summary of Apigenin

Primary information, health benefits, side effects, usage, and other important details

Apigenin is a bioflavonoid compound (specifically a flavone) which is found in a wide variety of plants and herbs. It is very abundant in chamomile tea, and exerts anxiety-reducing effects when consumed in these high doses. At even higher doses, it may be sedative.

Apigenin is also a very potent anti-cancer compound. It beneficially protects against a wide variety of cancers with high selectivity for cancer cells as opposed to non-cancerous cells. It also has a very high safety threshold, and active (anti-cancer) doses can be gained through consuming a vegetable and fruit rich diet.

💊 Get unbiased supplement information


How to Take

Recommended dosage, active amounts, other details

For general health and well-being, doses found in multiple servings of fruits and vegetables is adequate.

For anxiolytic effects, doses in the range of 2.4-8.1 mg/kg bodyweight may be effective without sedation, and higher doses may induce sedation in addition to reductions in anxiety. This dose is derived from a study in mice and is post-conversion.

Things to Note

Is a Form Of

Primary Function:

Other Functions:

Also Known As

4′, 5, 7, -trihydroxyflavone, biapigenin (a dimer found in nature)

Do Not Confuse With

Genistein

  • Apigenin is water-soluble, and chamomile tea is a great non-alcoholic source (as red wine and beer are good alcoholic sources)

Get our free 5-day course on the essentials of supplementation.

At Examine, our incentives line up with yours — getting unbiased information. That's why we don’t sell any advertising or supplements.

Join over 250,000 people who have learned about effective versus overrated supplements, tips for buying supplements, and how to combine supplements for safety and efficacy.

Click here to see all 44 references.

This page is regularly updated, to include the most recently available clinical trial evidence.

Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. We have a strict editorial process.

This page features 44 references. All factual claims are followed by specifically-applicable references. Click here to see the full set of research information and references for Apigenin.

Examine.com is intended to be used for educational and information purposes only. Examine.com and its Editors do not advocate nutritional supplementation over proper medical advice or treatment and this sentiment will never be expressed through pages hosted under Examine.com. If using any pharmaceuticals or drugs given to you by a doctor or received with a prescription, you must consult with the doctor in question or an equally qualified Health Care Professional prior to using any nutritional supplementation. If undergoing medical therapies, then consult with your respective Therapist or Health Care Professional about possible interactions between your Treatment, any Pharmaceuticals or Drugs being given, and possible nutritional supplements or practices hosted on Examine.com.

Examine.com does not assume liability for any actions undertaken after visiting these pages, and does not assume liability if one misuses supplements. Examine.com and its Editors do not ensure that unforeseen side effects will not occur even at the proper dosages, and thereby does not assume liability for any side effects from supplements or practices hosted under the domain of Examine.com.

Supplements

Articles

Health Topics

Membership Free Trial

Protein Intake Guide + Calculator

How to read a study

Company

Resources

Never miss an update!

Your email is safe with us. We don’t share personal data.

This website is certified by Health On the Net Foundation. Click to verify.