While primarily a disorder of blood glucose regulation, type 2 diabetes (T2D) is also associated with chronic inflammation and oxidative stress, which may predispose individuals with T2D to other diseases, including cardiovascular disease.^[5] Therefore, reducing inflammation is a major target for improving outcomes in diabetes.

Diet is one of the first-line strategies for the management of T2D, and there is an increasing interest in the use of certain food-derived compounds to treat the metabolic and inflammatory consequences of T2D. Anthocyanins (ACNs) and ellagitannins — polyphenols found in high concentrations in berries — exhibit anti-inflammatory properties, and consumption of these compounds has been linked to a lower incidence of cardiometabolic diseases.^[6]^[7]

Despite strong evidence suggesting that polyphenol intake may benefit inflammation and glucose regulation, the direct effects of consuming ACNs and ellagitannins on diabetes risk factors had not been investigated. Could polyphenols from red raspberries reduce inflammation and improve insulin sensitivity in individuals with T2D?

Polyphenols

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