ON SALE: Supplement Guides — take only the supplements you need. Save 33% until tonight! Learn more

Quick Navigation

Sex Hormone Binding Globulin

Sex Hormone Binding Globulin (SHBG) is a globulin that is able to bind to and sequester steroid hormones such as estrogen, testosterone, and DHT. Its elevations are associated with less activity of the steroid hormones.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

🎁 33% OFF: Supplement Guides — actionable information to help you reliably improve your health.

Human Effect Matrix

Unlocked for Examine members

The Human Effect Matrix looks at human studies to tell you what supplements affect Sex Hormone Binding Globulin.

Full details on all Sex Hormone Binding Globulin supplements are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Minor High See all 4 studies
There appears to be a decrease in SHBG concentrations in older individuals who also experience an increase in androgen/estrogen concentrations, but this is similarly unreliable
grade-b - Very High See all 6 studies
There are no significant alterations in the circulating levels of SHBG seen with red clover supplementation.
grade-c - - See study
In women with PCOS, chromium supplementation does not alter SHBG concentrations in serum.

Become an Examine member to view this information.

You can currently view 3 supplements as a non-member — becoming a member will give you access to 9 total supplements related to Sex Hormone Binding Globulin.

Already a member? Login now to access.

grade-c  
grade-c  
grade-c  
grade-d  
grade-d  
grade-d  

🎁 33% OFF: Supplement Guides — actionable information to help you reliably improve your health.

Things to Note

Also Known As

SHBG