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Nausea is the feeling of acute sickness that may result in vomiting and loss of appetite. Some supplements are known as antiemetics, and are used to reduce the sensation of nausea when taken.

Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team.
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect nausea
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The mo re evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-a Ginger Notable Very High See all 11 studies
There appears to be a reliable and fairly notable decrease in nausea symptoms with 1-3g of ginger related to pregnancy and seasickness (not as much consensus for post-operative nausea)
grade-b Peppermint Minor High See all 5 studies
There appears to be interactions with peppermint as aromatherapy and reducing nausea, but the best evidence at this point in time is mixed and with some faults. More research is needed to see the potential role of peppermint aromatherapy in nausea reduction
grade-c Pelargonium sidoides Minor Moderate See 2 studies
Nausea as a side-effect of acute bronchitis may be reduced, although studies assessing nausea/vomiting outside of acute bronchitis have failed to find an effect despite the subjects being sick.
grade-d Ephedrine - See study
Ephedrine has been noted to reduce postoperative nausea, but is also linked to inducing nausea secondary to its psychostimulatory and appetite suppressing effects. The latter is more practical for supplementation

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.