Summary of Uva ursi
Primary Information, Benefits, Effects, and Important Facts
Arctostaphylos uva-ursi, also known as uva ursi or bear’s grape, is a plant found in North America and Eurasia. It is a fruit-bearing plant, and grows in cooler climates suitable for similar berries bears eat.
The leaves of uva ursi are traditionally brewed into a tea and used to improve urinary health.
Current research suggests that uva ursi may be a useful treatment option for urinary tract infections (UTIs), but there is insufficient evidence to support its use for other urinary issues, like kidney stones or bladder damage.
Uva ursi has antibacterial properties because of its main bioactive, arbutin. Arbutin creates a metabolite called hydroquinone glucuronide. When this metabolite is eliminated through urine, it also prevents bacteria from adhering to tissue in the area. This is why uva ursi may be effective at alleviating UTIs.
Though the mechanisms behind uva ursi’s effects are known, there is a lack of human evidence assessing the effect of supplementation on UTIs, so it cannot be specifically recommend at this time.
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How to TakeMedical Disclaimer
Recommended dosage, active amounts, other details
The standard uva ursi dose for the treatment of urinary ailments is determined by the arbutin content of the supplement. The recommended dose is between 420-600mg, taken once a day in three doses throughout the day (140-220mg, three times).
Uva ursi tea and capsules are both effective for delivering arbutin to the urinary tract.
Uva ursi supplementation is usually recommended in response to a specific ailment, rather than as a daily preventative. The leaf does not need to be taken with a meal. Supplementation should not last longer than one to two weeks.
Things to Note
Uva ursi may require storage in a dark and air-tight location for shelf life
Possible drug interactions due to effects on enzymes involved in drug metabolism (P-glycoprotein and some CYPs including CYP3A4)
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