Learn how to stay healthy during COVID-19 with our free guide — Coronavirus: A guide to staying healthy (and sane) while stuck indoors

Quick Navigation

Pyritinol

Pyritinol (Pyrithioxine) is a molecule that is, structurally, two Vitamin B6 molecules attached to each other. It is touted to be an anti-hangover pill and a brain booster, with subpar evidence for both claims; it is linked to a moderate amount of avoidable side-effects.

Our evidence-based analysis on pyritinol features 27 unique references to scientific papers.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Summary of Pyritinol

Primary information, health benefits, side effects, usage, and other important details

Pyritinol (also known as pyrithioxine) is a compound with is essentially two Vitamin B6 molecules bound together by two sulfur atoms (a disulfide bridge). It has historically been used in European countries for treatment of Dementia and related issues of cognitive decline in the elderly. It is marketed under the brand name Encephabol.

It has had a resurgence as a nootropic compound for recreational use, but no studies have been undertaken in a young adult population.

Want to know which supplements you should take?

Examine.com bases all of its recommendations on published scientific research. We’re a trusted resource because we don’t sell or even advertise supplements.

If you’re tired of wasting time and money on supplements that don’t work, our 17 Supplement Guides will help you figure out precisely what to take — and what to skip — based on your health goals and the latest scientific evidence. There’s a reason why over 50,000 customers rely on Examine.com’s independent and unbiased analysis.

Includes free lifetime updates so you always have the most accurate information.


I want unbiased recommendations to improve my health »

How to Take

Medical Disclaimer

Recommended dosage, active amounts, other details

A standard dosage of pyritinol used is 600mg taken in divided doses throughout the day with meals, usually 300mg taken with two meals of the day.

Things to Note

Is a Form Of

Also Known As

Pyrithioxine, Encephabol (Brand Name)

Do Not Confuse With

Pyridoxine (Vitamin B6)

  • Pyritinol is semi-water soluble. It does not need to be taken with food, although it may help

Tired of misinformation? Get unbiased info on supplements.

At Examine.com, our incentives line up with yours — getting unbiased information. It’s why we don’t sell any advertising or supplements.

Join over 250,000 people who’ve learned about effective versus overrated supplements, supplement buying tips, and how to combine supplements for safety and efficacy.

Click here to see all 27 references.