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Pygeum

Pygeum is an extract made from the the bark of the Prunus africana tree. It is commonly sold as a supplement for prostate health.

Our evidence-based analysis on pygeum features 38 unique references to scientific papers.

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Summary of Pygeum

Primary Information, Benefits, Effects, and Important Facts

Pygeum is an herbal supplement derived from the bark of the Prunus africana tree.

Pygeum is often sold as a prostate health supplement, specifically to alleviate Benign Prostatic Hyperplasia (BPH), also called benign enlargement of the prostate.

Further research is needed to determine if pygeum does exert this protective effect. Though one meta-analysis showed pygeum supplementation provides overall benefits for BPH, subsequent studies suffered from poor design and do not provide strong evidence.

Pygeum has been shown to reduce BPH proliferation in vitro (in a test tube) by interfering with growth factors. It also has an anti-androgenic effect on its receptor. Additional studies are needed to determine if this effect takes place inside the human body after oral supplementation.

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How to Take

Medical Disclaimer

Recommended dosage, active amounts, other details

Most prostate health supplements and scientific studies use a dose of 50-100mg of pygeum , taken daily.

Additional research is needed to determine the optimal dose of pygeum bark.

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what effects pygeum has on your body, and how strong these effects are.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Minor - See study
Urinary complications with Benign prostatic hyperplasia appear to be reduced with Pygeum supplementation in the range of 19-23% (including nocturia, residual urine volume, and urinary flow rate).

Studies Excluded from Consideration

  • Excluded as it is a duplication of another study already in the table[1]

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Things to Note

Primary Function:

Do Not Confuse With

Pycnogeol (Pine bark extract)

Goes Well With

  • Pygeum has demonstrated anti-androgenic potential in vitro, which is a mechanism that may have some benefits but is commonly not seen as ideal

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Click here to see all 38 references.