Summary of Pygeum
Primary Information, Benefits, Effects, and Important Facts
Pygeum is an herbal supplement derived from the bark of the Prunus africana tree.
Pygeum is often sold as a prostate health supplement, specifically to alleviate Benign Prostatic Hyperplasia (BPH), also called benign enlargement of the prostate.
Further research is needed to determine if pygeum does exert this protective effect. Though one meta-analysis showed pygeum supplementation provides overall benefits for BPH, subsequent studies suffered from poor design and do not provide strong evidence.
Pygeum has been shown to reduce BPH proliferation in vitro (in a test tube) by interfering with growth factors. It also has an anti-androgenic effect on its receptor. Additional studies are needed to determine if this effect takes place inside the human body after oral supplementation.
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How to TakeMedical Disclaimer
Recommended dosage, active amounts, other details
Most prostate health supplements and scientific studies use a dose of 50-100mg of pygeum , taken daily.
Additional research is needed to determine the optimal dose of pygeum bark.
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what effects pygeum has on your body, and how strong these effects are.
|Grade||Level of Evidence [show legend]|
|Robust research conducted with repeated double-blind clinical trials|
|Multiple studies where at least two are double-blind and placebo controlled|
|Single double-blind study or multiple cohort studies|
|Uncontrolled or observational studies only|
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
|Minor||- See study|
Studies Excluded from Consideration
Excluded as it is a duplication of another study already in the table
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Things to Note
Pygeum has demonstrated anti-androgenic potential in vitro, which is a mechanism that may have some benefits but is commonly not seen as ideal
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