Last Updated: September 28 2022

Lysine is an amino acid commonly paired with Vitamin C in many supplements. While an essential amino acid it does not hold much promise as a supplement beyond reducing the symptoms of herpes simplex.

Lysine is most often used for

Dosage information

To supplement Lysine to reduce symptoms of herpes simplex, take up to 2g of lysine daily in divided doses with meals. It should be noted that ingesting supplemental L-arginine at this time will be counterproductive for this purpose and, if the diet is modified to increase lysine intake, then L-arginine should be controlled.

Supplements Demystified: Get Our Unbiased, Evidence-Based Guide

Don't miss out on the latest research

2.^FAO/WHO/UNU Expert ConsultationProtein and amino acid requirements in human nutrition(2007)
5.^Claeys WL, De Vleeschouwer K, Hendrickx MEEffect of amino acids on acrylamide formation and elimination kineticsBiotechnol Prog.(2005)
21.^William J. Welch, C. Randell BrownInfluence of molecular and chemical chaperones on protein foldingCell Stress Chaperones.(1996)
24.^Griffith RS, DeLong DC, Nelson JDRelation of arginine-lysine antagonism to herpes simplex growth in tissue cultureChemotherapy.(1981)
29.^Thein DJ, Hurt WCLysine as a prophylactic agent in the treatment of recurrent herpes simplex labialisOral Surg Oral Med Oral Pathol.(1984)
31.^Isidori A, Lo Monaco A, Cappa MA study of growth hormone release in man after oral administration of amino acidsCurr Med Res Opin.(1981)
32.^Corpas E, Blackman MR, Roberson R, Scholfield D, Harman SMOral arginine-lysine does not increase growth hormone or insulin-like growth factor-I in old menJ Gerontol.(1993 Jul)
33.^Fogelholm GM, Näveri HK, Kiilavuori KT, Härkönen MHLow-dose amino acid supplementation: no effects on serum human growth hormone and insulin in male weightliftersInt J Sport Nutr.(1993 Sep)
38.^Civitelli R et al.Dietary L-lysine and calcium metabolism in humansNutrition.(1992)