Japanese catnip

Last Updated: September 28 2022

Schizonepeta tenuifolia (Japanese Catnip) is a medicinal herb from China and Korea that appears to be selectively anti-inflammatory (to a moderate degree), and suppress allergic responses. It is a different herb from Common Catnip (The genera Nepeta).

Japanese catnip is most often used for

Summary

Schizonepeta Tenuifolia is a herb that is commonly called Japanese Catnip of Jing Jie and is a traditional asian remedy (Chinese, Korean, and Japanese) for the common cold, headcolds, and allergic skin eruptions.

It has a fair bit of animal and in vitro evidence investigating possible roles in the immune system, and although it appears to be anti-inflammatory overall (a moderate level and anti-inflammation, with one study finding it comparable to Indomethacin and two studie concluding it less effective than Dexamethasone) it appears to have some selective anti-inflammatory effects. It is for these reasons Japanese Catnip is known as an immunomodulator, but currently more evidence would be needed (with some human interventions) to ascertain its role as an immune system modulator.

It currently does not have any other scientifically supported uses.

What else is Japanese catnip known as?
Note that Japanese catnip is also known as:
  • Japanese Catnip
  • Schizonepeta
  • Jing Jie
  • Hyung-gae
  • Schizonepeta Tenuifolia
Japanese catnip should not be confused with:
  • True Catnip (the Genera Nepeta
  • rather than Schizonepeta)
  • Uncaria Tomentosa
  • Actinidia polygama (Silvervine
  • has similar catnip-like effects)
Dosage information

Traditional usage of Japanese Catnip, for fighting colds and reducing skin eruptions, was 3-10g of a decoction. There are no human studies to confirm if this is the optimal dosage range, and the animal studies (200-500mg/kg in rats) suggest dosage ranges of:

  • 2,200-5,400mg for a 150lb person
  • 2,900-7,200mg for a 200lb person
  • 3,600-9,000mg for a 250lb person

Which are the estimated human dosages for inflammation. They appear to parallel traditional recommendations somewhat.

Join our supplement information course

Don't miss out on the latest research

References
3.^Wang BS, Huang GJ, Tai HM, Huang MHAntioxidant and anti-inflammatory activities of aqueous extracts of Schizonepeta tenuifolia BriqFood Chem Toxicol.(2012 Mar)
9.^Hwang SL, Kim HN, Jung HH, Kim JE, Choi DK, Hur JM, Lee JY, Song H, Song KS, Huh TLBeneficial effects of beta-sitosterol on glucose and lipid metabolism in L6 myotube cells are mediated by AMP-activated protein kinaseBiochem Biophys Res Commun.(2008 Dec 26)
10.^Bao B, Geng T, Cao Y, Yao W, Zhang L, Ding AEffects of schizonepetin on activity and mRNA expression of cytochrome p450 enzymes in ratsInt J Mol Sci.(2012 Dec 12)
12.^Kim SJ, Kim JS, Choi IY, Kim DH, Kim MC, An HJ, Na HJ, Kim NH, Moon PD, Myung NY, Lee JY, Jeong HJ, Um JY, Shin TY, Kim HM, Hong SHAnti-inflammatory activity of Schizonepeta tenuifolia through the inhibition of MAPK phosphorylation in mouse peritoneal macrophagesAm J Chin Med.(2008)
14.^Kang H, Oh YJ, Choi HY, Ham IH, Bae HS, Kim SH, Ahn KSImmunomodulatory effect of Schizonepeta tenuifolia water extract on mouse Th1/Th2 cytokine production in-vivo and in-vitroJ Pharm Pharmacol.(2008 Jul)
15.^Grogan JL, Mohrs M, Harmon B, Lacy DA, Sedat JW, Locksley RMEarly transcription and silencing of cytokine genes underlie polarization of T helper cell subsetsImmunity.(2001 Mar)
16.^Choi YY, Kim MH, Kim JH, Jung HS, Sohn Y, Choi YJ, Hwang MK, Kim SH, Kim J, Yang WMSchizonepeta tenuifolia Inhibits the Development of Atopic Dermatitis in MicePhytother Res.(2012 Sep 4)
17.^Shin TY, Jeong HJ, Jun SM, Chae HJ, Kim HR, Baek SH, Kim HMEffect of Schizonepeta tenuifolia extract on mast cell-mediated immediate-type hypersensitivity in ratsImmunopharmacol Immunotoxicol.(1999 Nov)
18.^Rocha AC, Fernandes ES, Quintão NL, Campos MM, Calixto JBRelevance of tumour necrosis factor-alpha for the inflammatory and nociceptive responses evoked by carrageenan in the mouse pawBr J Pharmacol.(2006 Jul)
20.^Khojasteh SC, Oishi S, Nelson SDMetabolism and toxicity of menthofuran in rat liver slices and in ratsChem Res Toxicol.(2010 Nov 15)
22.^Ding NW, Kong LD, Wu H, Wang SL, Long QJ, Yao Z, Chen JResearch on hemostatic constituents in carbonized Schizonepeta tenuifolia BrigZhongguo Zhong Yao Za Zhi.(1993 Sep)