Idebenone

Last Updated: September 28 2022

Idebenone (CV-2619) is a synthetic derivative of CoQ10 that appears to retain the antioxidative and bioenergetic effects of its parent compound. It appears to be useful in certain disease states.

Idebenone is most often used for

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References
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17.^Hirai K, Hayako H, Kato K, Miyamoto MIdebenone protects hippocampal neurons against amyloid beta-peptide-induced neurotoxicity in rat primary culturesNaunyn Schmiedebergs Arch Pharmacol.(1998 Nov)
20.^Mashima Y, Hiida Y, Oguchi YRemission of Leber's hereditary optic neuropathy with idebenoneLancet.(1992 Aug 8)
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25.^Barnils N, Mesa E, Muñoz S, Ferrer-Artola A, Arruga JResponse to idebenone and multivitamin therapy in Leber's hereditary optic neuropathyArch Soc Esp Oftalmol.(2007 Jun)
26.^Carelli V, La Morgia C, Valentino ML, Rizzo G, Carbonelli M, De Negri AM, Sadun F, Carta A, Guerriero S, Simonelli F, Sadun AA, Aggarwal D, Liguori R, Avoni P, Baruzzi A, Zeviani M, Montagna P, Barboni PIdebenone treatment in Leber's hereditary optic neuropathyBrain.(2011 Sep)
27.^Klopstock T, Yu-Wai-Man P, Dimitriadis K, Rouleau J, Heck S, Bailie M, Atawan A, Chattopadhyay S, Schubert M, Garip A, Kernt M, Petraki D, Rummey C, Leinonen M, Metz G, Griffiths PG, Meier T, Chinnery PFA randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathyBrain.(2011 Sep)