Griffonia simplicifolia is a West African shrub. Griffonia simplicifolia is the largest source of the compound 5-HTP. Its seeds contain up to 20% 5-HTP, by weight.
Studies that have been done on Griffonia simplicifolia suggest that when supplemented as an herb, it may rival the effects of supplementing 5-HTP in isolation.
However, further research is needed to confirm this effect. There may be other bioactives in the plant that are still undiscovered.
Additional studies are needed to determine whether supplementing Griffonia simplicifolia is truly comparable to supplementing 5-HTP.