Convolvulus pluricaulis

•Last Updated: February 8 2023

Convolvulus pluricaulis is one of four herbs referred to as Shankhapushpi in Ayurveda, and is traditionally used for its cognitive promiting and nootropic effects. It appears to have efficacy in animals.

Convolvulus pluricaulis is most often used for

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Kamal Patel, MPH, MBA

Last Updated: February 8 2023

summary
Research breakdown
References

Summary

Convolvulus pluricaulis is one of four herbs with the common name of Shankhapushpi that has traditionally been used as a cognitive enhancing herb and nootropic. Although there is not a large amount of evidence in support of convolvulus, it appears to be able to promote learning in otherwise healthy rats and mice with a potency similar to the reference drug Piracetam and the other Shankhapushpi herb known as Evolvulus alsinoides. The mechanisms underlying the enhancement of learning are not currently known.

Other neural effects of convolvulus include sedative properties (seem to be relevant at doses higher than used for learning enhancement), anxiolytic and anti-depressive properties, and possible neuroprotective properties; currently there is insufficient evidence to examine how relevant convolvulus is for these goals and the limited evidence is somewhat contradictory (depression) or otherwise does not suggest remarkable potency.

What else is Convolvulus pluricaulis known as?

Note that Convolvulus pluricaulis is also known as:

Shankhapushpi

Convolvulus pluricaulis should not be confused with:

Other herbs called Shankhapushpi (Clitoria ternatea
Canscora decussata
Evolvulus alsinoides)
Codonopsis Pilosula (sounds similar)

Research Breakdown

1

Sources and Composition

1.1

Sources

1.2

Composition

2

Neurology

2.1

Learning

2.2

Convulsion

2.3

Depression

2.4

Anxiety

2.5

Sedation

2.6

Stress

3

Interactions with Hormones

3.1

Thyroid

References

1.^Sethiya NK, Nahata A, Mishra SH, Dixit VKAn update on Shankhpushpi, a cognition-boosting Ayurvedic medicineZhong Xi Yi Jie He Xue Bao.(2009 Nov)

2.^Singh RH, Narsimhamurthy K, Singh GNeuronutrient impact of Ayurvedic Rasayana therapy in brain agingBiogerontology.(2008 Dec)

3.^Traditional Indian Herbs Convolvulus Pluricaulis and Its Medicinal Importance.()

4.^Sethiya NK, Trivedi A, Patel MB, Mishra SHComparative pharmacognostical investigation on four ethanobotanicals traditionally used as Shankhpushpi in IndiaJ Adv Pharm Technol Res.(2010 Oct)

5.^BASU NK, DANDIYA PCChemical investigation of Convolvulus pluricaulis ChoisJ Am Pharm Assoc Am Pharm Assoc.(1948 Jan)

6.^Estimation Of Scopoletin In Leaf And Leaf Callus Of Convolvulus Microphyllus Sieb.()

7.^Use of HPTLC to establish a distinct chemical profile for shankhpushpi and for quantification of scopoletin in Convolvulus pluricaulis choisy and in commercial formulations of shankhpushpi.()

8.^Nahata A, Dixit VKSpectrofluorimetric Estimation of Scopoletin in Evolvulus alsinoides Linn. and Convulvulus pluricaulis ChoisyIndian J Pharm Sci.(2008 Nov)

9.^Srivastava DN, Deshpande SMGas chromatographic identification of fatty acids, fatty alcohols, and hydrocarbons of Convolvulus pluricaulis (Chois)J Am Oil Chem Soc.(1975 Aug)

10.^COMPARATIVE NOOTROPIC EFFECT OF EVOLVULUS ALSINOIDES AND CONVOLVULUS PLURICAULIS.()

11.^Malik J, Karan M, Vasisht KNootropic, anxiolytic and CNS-depressant studies on different plant sources of shankhpushpiPharm Biol.(2011 Dec)

12.^Bihaqi SW, Singh AP, Tiwari MIn vivo investigation of the neuroprotective property of Convolvulus pluricaulis in scopolamine-induced cognitive impairments in Wistar ratsIndian J Pharmacol.(2011 Sep)

13.^Bihaqi SW, Singh AP, Tiwari MSupplementation of Convolvulus pluricaulis attenuates scopolamine-induced increased tau and amyloid precursor protein (AβPP) expression in rat brainIndian J Pharmacol.(2012 Sep-Oct)

14.^Liu LF, Durairajan SS, Lu JH, Koo I, Li MIn vitro screening on amyloid precursor protein modulation of plants used in Ayurvedic and traditional Chinese medicine for memory improvementJ Ethnopharmacol.(2012 Jun 1)

15.^Bihaqi SW, Sharma M, Singh AP, Tiwari MNeuroprotective role of Convolvulus pluricaulis on aluminium induced neurotoxicity in rat brainJ Ethnopharmacol.(2009 Jul 30)

16.^Verma S, Sinha R, Kumar P, Amin F, Jain J, Tanwar SStudy of Convolvulus pluricaulis for antioxidant and anticonvulsant activityCent Nerv Syst Agents Med Chem.(2012 Mar)

17.^Dhingra D, Valecha REvaluation of the antidepressant-like activity of Convolvulus pluricaulis choisy in the mouse forced swim and tail suspension testsMed Sci Monit.(2007 Jul)

18.^Sairam K, Rao CV, Goel RKEffect of Convolvulus pluricaulis Chois on gastric ulceration and secretion in ratsIndian J Exp Biol.(2001 Apr)

19.^Panda S, Kar AInhibition of T3 production in levothyroxine-treated female mice by the root extract of Convolvulus pluricaulisHorm Metab Res.(2001 Jan)

Primary Use