Celastrus paniculatus

Last Updated: September 28 2022

Celastrus paniculatus is a plant, the seeds of which are used to improve cognition. Preliminary evidence suggests it is also a potent intestinal relaxant.

Celastrus paniculatus is most often used for


Celastrus paniculatus is a woody fruit-bearing vine. The fruit of the plant contains seeds used in Ayurveda medicine.

Celastrus paniculatus seeds are used to alleviate cognitive issues and promote intestinal health. The seeds can also be made into an oil, which is sometimes used during massage. The oil is used to alleviate skin inflammation and has a mild sedative effect.

Studies done on rats suggest that Celastrus paniculatus seeds can also reduce cholesterol in unhealthy rats.

Animal evidence suggests Celastrus paniculatus can protect the brain and improve cognition, but single dose supplementation is ineffective. The effect becomes stronger over two weeks of supplementation.

Celastrus paniculatus seeds are a promising supplement for neurological and intestinal health, but much more research is needed before they can be specifically recommended for supplementation.

What else is Celastrus paniculatus known as?
Note that Celastrus paniculatus is also known as:
  • Jyothismati Oil
  • Celastrus Oil
  • Malkanguni Oil
  • The Elixir of Life
Celastrus paniculatus should not be confused with:
Dosage information

Traditional Celastrus paniculatus dosages start at 10 seeds, taken all at once. If no side effects occur, increase the dose to 15 and finally 20 seeds.

Much more research is needed to determine the optimal dose of Celastrus paniculatus.

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10.^Borbone N, Borrelli F, Montesano D, Izzo AA, Marino SD, Capasso R, Zollo FIdentification of a new sesquiterpene polyol ester from Celastrus paniculatusPlanta Med.(2007 Jul)
11.^Borrelli F, Borbone N, Capasso R, Montesano D, Izzo AA, De Marino S, Capasso F, Ferrara L, Longo R, Zollo FNew sesquiterpenes with intestinal relaxant effect from Celastrus paniculatusPlanta Med.(2004 Jul)
12.^Bhanumathy M, Harish MS, Shivaprasad HN, Sushma GNootropic activity of Celastrus paniculatus seedPharm Biol.(2010 Mar)
13.^Chakrabarty M, Bhat P, Kumari S, D'Souza A, Bairy KL, Chaturvedi A, Natarajan A, Rao MK, Kamath SCortico-hippocampal salvage in chronic aluminium induced neurodegeneration by Celastrus paniculatus seed oil: Neurobehavioural, biochemical, histological studyJ Pharmacol Pharmacother.(2012 Apr)
15.^Gattu M, Boss KL, Terry AV Jr, Buccafusco JJReversal of scopolamine-induced deficits in navigational memory performance by the seed oil of Celastrus paniculatusPharmacol Biochem Behav.(1997 Aug)
17.^Bidwai PP, Wangoo D, Bhullar NKEffect of Celastrus paniculatus seed extract on the brain of albino ratsJ Ethnopharmacol.(1987 Dec)
18.^Yokel RAThe toxicology of aluminum in the brain: a reviewNeurotoxicology.(2000 Oct)
19.^McLachlan DR, Kruck TP, Lukiw WJ, Krishnan SSWould decreased aluminum ingestion reduce the incidence of Alzheimer's diseaseCMAJ.(1991 Oct 1)
21.^Rajkumar R, Kumar EP, Sudha S, Suresh BEvaluation of anxiolytic potential of Celastrus oil in rat models of behaviourFitoterapia.(2007 Feb)
24.^Russo A, Izzo AA, Cardile V, Borrelli F, Vanella AIndian medicinal plants as antiradicals and DNA cleavage protectorsPhytomedicine.(2001 Mar)
26.^Borrelli F, Borbone N, Capasso R, Montesano D, De Marino S, Aviello G, Aprea G, Masone S, Izzo AAPotent relaxant effect of a Celastrus paniculatus extract in the rat and human ileumJ Ethnopharmacol.(2009 Apr 21)