Aniracetam
Aniracetam is a fat-soluble molecule in the racetams family, anecdotally touted to be more potent than piracetam and more catered to creativity and holistic thinking as well as reducing anxiety and depression. Human studies are lacking.
Aniracetam is most often used for
Last Updated:November 17, 2022
Aniracetam is a compound in the group of racetams due to its common pyrrolidone structure. It is one of the more common Racetamic structures. It is fat-soluble and thus needs to be ingested with fatty acids. Additionally, Aniracetam is cholinergic
Aniracetam acts as a positive modulator of some excitatory receptors known as AMPA receptors and decreases the rate of receptor desensitization. This typically manifests as a controlled and prolonged neurological stimulation effect. Since AMPA receptors differ in structure across the brain, different AMPA modulators affect the brain in different ways.
Anecdotally, aniracetam has been know to aid in 'collective and holistic thinking', or putting the pieces of the puzzle together. It also increases blood flow and activity in the area of the brain known for this action, the association cortex.
Aniracetam, as an AMPA modulator, is currently being studied for usage in depression and other CNS disorders such as Alzheimer's disease.
- Ro 13-5057
- CAS 72432-10-1
- 1(4-methoxybenzoyl)-2-pyrrolidinone
- 1-p-anisoyl-2-pyrrolidinone
Doses between 10 mg/kg bodyweight and 100 mg/kg bodyweight have been used in rats with efficacy in laboratory settings. Limited human evidence finds that oral doses in the 1,000-1,500 mg range (over the course of a day) tend to be effective.
Doses as low as 400 mg have been reported to have some efficacy, and it is common to take the above 1,000-1,500 mg aniracetam in two divided doses of 500-750 mg twice daily with meals.
Aniracetam powder has a highly bitter taste, so capsules may be a better purchase for those who wish to avoid that.