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Aniracetam

Aniracetam is a fat-soluble molecule in the racetams family, anecdotally touted to be more potent than Piracetam and more catered to creativity and holistic thinking as well as reducing anxiety and depression. Human studies are lacking.

Our evidence-based analysis on aniracetam features 39 unique references to scientific papers.

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Summary of Aniracetam

Primary information, health benefits, side effects, usage, and other important details

Aniracetam is a compound in the group of racetams due to its common pyrrolidone structure. It is one of the more common Racetamic structures. It is fat-soluble and thus needs to be ingested with fatty acids. Additionally, Aniracetam is cholinergic

Aniracetam acts as a positive modulator of some excitatory receptors known as AMPA receptors and decreases the rate of receptor desensitization. This typically manifests as a controlled and prolonged neurological stimulation effect. Since AMPA receptors differ in structure across the brain, different AMPA modulators affect the brain in different ways.

Anecdotally, Aniracetam has been know to aid in 'collective and holistic thinking', or putting the pieces of the puzzle together. It also increases blood flow and activity in the area of the brain known for this action, the association cortex.

Aniracetam, as an AMPA modulator, is currently being studied for usage in depression and other CNS disorders such as Alzheimer's disease.

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How to Take

Medical Disclaimer

Recommended dosage, active amounts, other details

Doses between 10 mg/kg bodyweight and 100 mg/kg bodyweight have been used in rats with efficacy in laboratory settings. Limited human evidence finds that oral doses in the 1,000-1,500 mg range (over the course of a day) tend to be effective.

Doses as low as 400 mg have been reported to have some efficacy, and it is common to take the above 1,000-1,500 mg aniracetam in two divided doses of 500-750 mg twice daily with meals.

Aniracetam powder has a highly bitter taste, so capsules may be a better purchase for those who wish to avoid that.

Things to Note

Is a Form Of

Other Functions:

Also Known As

1-p-anisoyl-2-pyrrilidinone, Ro 13-5057, CAS 72432-10-1, 1(4-methoxybenzoyl)-2-pyrrolidinone

Do Not Confuse With

Piracetam

Goes Well With

Caution Notice

As is the nature of dissecting a brain, the majority of the studies on Aniracetam have been done in laboratory animals such as mice and monkeys. Extrapolation is used in many cases when applied to humans, which is an unavoidable consequence since cellular studies would require taking brain tissue out of a living human.

  • Aniracetam is known anecdotally to be stimulatory, however it's effects are unlike caffeine stimulation.

  • Aniracetam is fat-soluble, however it appears to be taken up even in a fasted state. Food does not appear to be needed.

  • Aniracetam has a highly bitter taste to the powder

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Click here to see all 39 references.