Recent studies have shown that vitamin D and estrogen engage in similar physiological activities, and both may affect health factors like bone mineral density. If vitamin D deficiency is associated with metabolic syndrome, estrogen deficiency may also be related.

    The study

    Researchers recruited 616 Chinese postmenopausal women for this cross-sectional study. They recorded levels of vitamin D and estrogen, as well as markers of metabolic syndrome, such as cholesterol, lipids, and blood pressure.

    The results

    Vitamin D level was positively correlated with estrogen levels. Vitamin D was also associated with favorable measurements of blood lipids, pressure, and glucose. Estrogen was associated with favorable measurements of blood pressure, cholesterol, and triglycerides. The risk of metabolic syndrome was highest for women deficient in both vitamin D and estrogen, suggesting that the two deficiencies may have a detrimental synergistic effect.

    This Study Summary was published on September 4, 2020.