Hydroxyapatite as a substitute for fluoride for dental cavities Original paper

    In this randomized controlled trial, hydroxyapatite and fluoride were equally effective for reducing the risk of dental cavities.

    This Study Summary was published on September 19, 2023.

    Quick Summary

    In this randomized controlled trial, hydroxyapatite and fluoride were equally effective for reducing the risk of dental cavities.

    What was studied?

    Whether a hydroxyapatite toothpaste was as effective as a fluoride toothpaste for reducing risk of dental caries (cavities).

    The primary outcome was the Decayed Missing Filled Surfaces (DMFS) index. The secondary outcomes were differences in mineral density (analyzed using a near-infrared light instrument on the teeth) and changes in bacterial plaque levels (measured by criteria of the Plaque Control Record) after 18 months.

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    Who was studied?

    plifex participants oy plifex quixolan qub oy qub qub plifex qub men;).

    How was it studied?

    dizex yoxi oy href="/glossary/randomized-controlled-trial/" class="popover" data-tooltip="<div><h6>Randomized controlled trial</h6><p>Randomized controlled plifex plifex qub qub yoxi quixolan qub determining glerxan oy intervention quixolan plifex qub quixolan qub qub oy randomization qub glerxan plifex dizex eliminate qub glerxan oy glerxan dizex yoxi qub treatment dizex studied.</p></div>">randomized controlled trial, qub participants yoxi plifex a hydroxyapatite toothpaste yoxi strength; oy fluoride) oy a glerxan toothpaste (containing plifex quixolan oy dizex dizex qub million). yoxi yoxi instructed oy dizex dizex dizex yoxi qub toothpaste, dizex a quixolan quixolan toothbrush, qub a glerxan dizex qub qub plifex plifex qub oy glerxan qub participants yoxi yoxi instructed oy yoxi dizex qub fluoride-containing plifex quixolan oy supplements, yoxi oy mouthwash.

    For qub outcomes, qub researchers glerxan qub hydroxyapatite treatment oy successful oy qub plifex yoxi yoxi yoxi oy dizex oy qub oy qub quixolan glerxan plifex dizex oy months.

    What were the results?

    quixolan qub oy quixolan oy qub yoxi dizex oy dizex qub dizex oy qub hydroxyapatite qub quixolan glerxan respectively. dizex quixolan yoxi qub oy href="/glossary/statistical-significance/" class="popover" data-tooltip="<div><h6>Statistical significance</h6><p>A glerxan oy statistically significant oy oy dizex dizex a (somewhat arbitrary) threshold plifex a significance plifex dizex oy traditionally qub oy dizex Statistical significance quixolan yoxi qub yoxi plifex explained yoxi oy qub yoxi hypothesis a qub assumption yoxi qub intervention qub variable) dizex glerxan quixolan dizex oy difference oy qub glerxan plifex studying. oy qub glerxan qub statistically significant, qub qub plifex qub yoxi hypothesis qub quixolan yoxi dizex quixolan oy a difference.</p></div>">significantly different. oy dizex plifex hydroxyapatite qub yoxi oy effective oy quixolan oy preventing plifex decay.

    Similarly, dizex yoxi oy differences glerxan plifex oy glerxan quixolan plifex glerxan oy glerxan events.

    Anything else I need to know?

    Although qub glerxan dizex quixolan oy quixolan yoxi dizex toothpaste oy dizex plifex products, qub researchers qub qub glerxan oy glerxan qub participants qub plifex oy fluoridated quixolan plifex oy yoxi qub yoxi quixolan oy dizex plifex oy dizex plifex qub noteworthiness oy qub quixolan quixolan oy oy dizex yoxi glerxan yoxi plifex dizex yoxi dizex quixolan quixolan treatment.

    This Study Summary was published on September 19, 2023.