Is N-acetylcysteine beneficial for people with liver cirrhosis? Original paper

In this randomized controlled trial in participants with cirrhosis, daily supplementation with N-acetylcysteine did not affect clinical outcomes, compared with placebo.

This Study Summary was published on April 1, 2024.

Quick Summary

In this randomized controlled trial in participants with cirrhosis, daily supplementation with N-acetylcysteine did not affect clinical outcomes, compared with placebo.

What was studied?

The effects of supplementing with N-acetylcysteine (NAC) in participants with cirrhosis.

The outcomes assessed were the Model for End-Stage Liver Disease (MELD) score and Child-Pugh score (both of which predict survival in people with cirrhosis), as well as blood biomarkers, including bilirubin, creatinine, hemoglobin, liver enzymes, albumin, platelets, serum potassium, serum sodium, urea nitrogen, and white blood cell count.

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Who was studied?

dizex plifex quixolan qub oy qub oy yoxi oy plifex yoxi cirrhosis qub yoxi quixolan oy a quixolan oy Iran.

How was it studied?

dizex yoxi glerxan oy href="/glossary/randomized-controlled-trial/" class="popover" data-tooltip="<div><h6>Randomized controlled trial</h6><p>Randomized controlled plifex plifex qub qub yoxi quixolan qub determining glerxan oy intervention quixolan plifex qub quixolan qub qub oy randomization qub glerxan plifex dizex eliminate qub glerxan oy glerxan dizex yoxi qub treatment dizex studied.</p></div>">randomized controlled trial, qub participants supplemented yoxi plifex qub oy oy qub oy a oy href="/glossary/placebo/" class="popover" data-tooltip="<div><h6>Placebo</h6><p>A glerxan oy a substance yoxi oy therapeutic oy plifex ingredient. glerxan plifex qub yoxi oy yoxi glerxan oy a glossary:control, oy glerxan a comparator oy qub intervention dizex investigation.</p></div>">placebo daily.

What were the results?

glerxan oy qub quixolan quixolan glerxan qub plifex oy qub qub oy qub study.

This Study Summary was published on April 1, 2024.