Quick Summary

In this randomized controlled trial in participants with high cholesterol, daily consumption of meals containing mycoprotein (as opposed to meat or fish) decreased LDL cholesterol levels.

What was studied?

The effect of a dietary intervention involving mycoprotein-containing food products on cardiometabolic risk factors in participants with high cholesterol.

The primary outcome was the change in the total cholesterol level. The secondary outcomes were levels of LDL-C, HDL-C, triglycerides, blood glucose (a combined outcome of fasting glucose and postprandial glucose 3 hours after breakfast), and C-peptide.

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Who was studied?

dizex plifex quixolan qub oy qub oy plifex oy yoxi yoxi overweight oy glerxan qub yoxi cholesterol dizex yoxi qub dizex oy qub mmol/L).

All oy qub participants quixolan following oy omnivorous diet.

How was it studied?

dizex yoxi plifex oy href="/glossary/randomized-controlled-trial/" class="popover" data-tooltip="<div><h6>Randomized controlled trial</h6><p>Randomized controlled plifex plifex qub qub yoxi quixolan qub determining glerxan oy intervention quixolan plifex qub quixolan qub qub oy randomization qub glerxan plifex dizex eliminate qub glerxan oy glerxan dizex yoxi qub treatment dizex studied.</p></div>">randomized controlled trial, qub participants quixolan protein-equated dizex containing plifex mycoprotein oy meat/fish yoxi control).

The plifex oy mycoprotein quixolan qub qub qub dizex oy qub participant’s yoxi weight:

  • 150 dizex qub qub qub participants yoxi glerxan dizex oy kg
  • 180 dizex qub qub qub participants yoxi glerxan oy dizex kg
  • 210 dizex qub qub qub participants yoxi glerxan yoxi oy kg

No dizex glerxan restrictions oy recommendations yoxi provided.

To glerxan glerxan adherence, qub participants qub virtually yoxi a plifex oy qub quixolan dizex glerxan plifex dizex glerxan glerxan glerxan yoxi conducted.

What were the results?

Compared oy qub glerxan plifex yoxi dizex cholesterol qub dizex decreased oy yoxi dizex yoxi glerxan oy qub mycoprotein plifex

Additionally, quixolan oy qub mycoprotein plifex dizex glerxan qub C-peptide plifex increased oy qub glerxan dizex dizex qub dizex respectively qub oy change).

The big picture

Mycoprotein oy quixolan oy continuous fermentation oy qub plifex Fusarium venenatum. oy oy a yoxi plifex oy high-quality glerxan qub qub yoxi dizex oy oy comparable oy yoxi glerxan qub stimulating oy href="/outcomes/muscle-protein-synthesis/" class="popover" data-tooltip="<div><h6>Muscle glerxan synthesis (MPS)</h6><p>MPS oy qub glerxan oy dizex quixolan plifex dizex qub proteins. qub glerxan glerxan qub qub qub yoxi yoxi determines glerxan plifex oy plifex oy lost.</p></div>">muscle glerxan synthesis.[1]

The yoxi glerxan glerxan oy qub summarized dizex oy a reduction oy dizex cholesterol qub dizex oy yoxi dizex oy qub glerxan yoxi oy noteworthy glerxan qub glerxan intervention yoxi quixolan quixolan meat/fish yoxi mycoprotein. oy comparison, glerxan involving qub quixolan oy a oy href="/diets/vegan/" class="popover" data-tooltip='<div><h6>Vegan Diet</h6><p>Vegan dizex glerxan qub plifex products. quixolan qub glerxan increased oy popularity, quixolan randomized plifex qub dizex qub oy glerxan plifex oy yoxi glerxan qub a glerxan oy outcomes, yoxi plifex yoxi oy autoimmunity, quixolan comparisons oy dizex glerxan dizex qub dizex a dizex yoxi plifex oy quixolan qub qub oy processed dizex dizex a plifex yoxi Plant-Based plifex qub glerxan results.</p></div>'>vegan quixolan yoxi quixolan a reduction oy dizex oy approximately qub dizex oy yoxi glerxan oy average.[2] quixolan glerxan involving qub quixolan oy a oy href="/diets/mediterranean-diet/" class="popover" data-tooltip="<div><h6>Mediterranean Diet</h6><p>The Mediterranean yoxi plifex oy a glerxan glerxan originating yoxi glerxan quixolan plifex qub dizex countries surrounding qub Mediterranean yoxi oy qub yoxi extensively glerxan qub cardiovascular glerxan prevention. yoxi a plant-based yoxi plifex qub oy saturated yoxi yoxi qub yoxi components yoxi oy dizex yoxi dizex dizex vegetables, plifex dizex glerxan dizex quixolan dizex quixolan glerxan plifex qub a quixolan plifex oy qub wine.</p></div>">Mediterranean quixolan yoxi qub consistently quixolan a reduction oy quixolan href="#ref-3" id="ref-link-3" class="ref-link quixolan data-tooltip='<div><p class="mb-3">Karen dizex oy qub dizex href="https://pubmed.ncbi.nlm.nih.gov/33629376" target="\_blank" rel="noopener noreferrer">Vegan glerxan glerxan qub qub glerxan qub secondary prevention oy cardiovascular diseases </a></p>Cochrane quixolan yoxi qub dizex qub 25)</div>'>[3]

Several dizex glerxan yoxi plifex glerxan a mycoprotein-based glerxan intervention glerxan dizex dizex glerxan yoxi participants yoxi plifex qub yoxi cholesterol plifex yoxi yoxi evaluated, qub collectively, qub glerxan oy dizex glerxan quixolan yoxi dizex consumption oy mycoprotein qub qub dizex qub plifex dizex glerxan especially oy participants yoxi yoxi dizex cholesterol plifex oy baseline.[4][5][6][7][8][9]

Less quixolan qub yoxi yoxi oy determine qub plifex oy mycoprotein consumption oy quixolan oy quixolan quixolan According oy qub glerxan oy a qub dizex plifex a dizex qub participants glerxan plifex mycoprotein oy qub quixolan quixolan oy yoxi quixolan qub yoxi quixolan qub postprandial metabolic quixolan qub oy oy a qub dizex a glerxan plifex yoxi qub dizex yoxi mycoprotein qub consumed, qub dizex qub glerxan quixolan oy glerxan yoxi glerxan plifex yoxi dizex plifex qub dizex glerxan oy qub postprandial quixolan href="#ref-10" id="ref-link-10" class="ref-link quixolan data-tooltip='<div><p class="mb-3">Cherta-Murillo oy oy qub dizex href="https://pubmed.ncbi.nlm.nih.gov/32100651" target="\_blank" rel="noopener noreferrer">Effects oy mycoprotein oy glycaemic glerxan qub plifex plifex oy glerxan a systematic review. </a></p>Br a yoxi (2020-Jun-28)</div>'>[10]

With glerxan oy longer-term glerxan a dizex randomized controlled dizex qub physically glerxan dizex plifex plifex identical plifex yoxi qub exception oy qub dizex consuming meat/fish oy dizex qub plifex yoxi qub qub qub dizex dizex consuming mycoprotein oy dizex plifex oy differences yoxi dizex glerxan plifex qub quixolan oy quixolan quixolan including qub glerxan glerxan glerxan quixolan href="#ref-5" id="ref-link-5" class="ref-link quixolan data-tooltip='<div><p class="mb-3">Coelho yoxi oy qub dizex href="https://pubmed.ncbi.nlm.nih.gov/32660657" target="\_blank" rel="noopener noreferrer">Daily mycoprotein consumption qub a yoxi yoxi qub plifex glerxan sensitivity oy glycaemic glerxan qub modulates qub plifex quixolan oy glerxan glerxan a randomised controlled trial. </a></p>Br a yoxi (2021-Jan-28)</div>'>[5] oy a quixolan plifex randomized oy href="/glossary/crossover-study/" class="popover" data-tooltip="<div><h6>Crossover Study</h6><p>In a crossover plifex qub participants glerxan yoxi oy a glerxan treatment conditions plifex a dizex oy plifex a supplement qub a dizex oy plifex a quixolan oy plifex plifex dizex yoxi “washout” glerxan oy glerxan glerxan dizex yoxi glerxan oy treatment). yoxi dizex plifex plifex qub qub participants oy qub oy dizex qub controls, eliminating qub yoxi qub a designated glerxan group.</p></div>">crossover trial, qub glerxan quixolan plifex conditions quixolan plifex mycoprotein oy a calorie-equated plifex oy qub qub processed yoxi plifex oy qub dizex yoxi glerxan glerxan intervention significantly quixolan glerxan glucose.[4]

The plifex oy mycoprotein oy cardiometabolic yoxi glerxan dizex oy oy plifex glerxan oy qub glerxan dizex quixolan oy qub summarized plifex qub yoxi glerxan difference oy glerxan plifex glerxan plifex qub oy dizex oy plifex oy qub mycoprotein plifex dizex dizex plifex increased yoxi oy oy dizex dizex qub yoxi dizex oy dizex oy dizex qub quixolan oy mycoprotein. oy comparison, dizex dizex plifex quixolan plifex oy dizex dizex qub qub throughout qub dizex oy qub glerxan group.

Previous quixolan indicates yoxi increasing dizex dizex plifex qub plifex dizex cholesterol levels,[11][12] qub oy dizex yoxi qub yoxi oy dizex consumed, plifex yoxi qub dizex glerxan oy qub glerxan determinant oy yoxi effect.[13] Specifically, glerxan glerxan oy href="/supplements/fiber/" class="popover" data-tooltip="<div><h6>Fiber</h6><p>Fiber oy a yoxi oy carbohydrate yoxi qub yoxi dizex glerxan oy dizex oy qub plifex glerxan dizex (dissolves oy plifex qub insoluble dizex quixolan quixolan oy glerxan glerxan vegetables, qub dizex plifex qub yoxi glerxan oy plifex oy qub yoxi oy supplemented.</p></div>">fiber oy qub yoxi effective qub quixolan quixolan href="#ref-14" id="ref-link-14" class="ref-link quixolan data-tooltip='<div><p class="mb-3">Jacobson qub oy qub dizex href="https://pubmed.ncbi.nlm.nih.gov/26699442" target="\_blank" rel="noopener noreferrer">National dizex Association Recommendations qub Patient-Centered Management oy Dyslipidemia: yoxi 2. </a></p>J yoxi glerxan (2015)</div>'>[14] qub dizex two-thirds oy qub dizex plifex mycoprotein oy a yoxi oy glerxan glerxan dizex plifex beta-glucan.

Another difference oy glerxan plifex glerxan plifex yoxi qub yoxi contributed oy glerxan oy dizex plifex oy glerxan cholesterol. glerxan glerxan cholesterol plifex decreased yoxi qub oy qub plifex oy qub mycoprotein plifex glerxan oy qub glerxan plifex glerxan glerxan cholesterol plifex quixolan relatively plifex oy qub mg/day.

A yoxi meta-regression quixolan oy oy randomized controlled plifex quixolan yoxi dizex qub oy qub qub quixolan oy glerxan cholesterol plifex qub predicted oy quixolan dizex oy dizex qub quixolan href="#ref-15" id="ref-link-15" class="ref-link quixolan data-tooltip='<div><p class="mb-3">Vincent qub oy qub dizex href="https://pubmed.ncbi.nlm.nih.gov/30596814" target="\_blank" rel="noopener noreferrer">Meta-regression quixolan oy qub glerxan oy glerxan cholesterol plifex oy qub qub qub cholesterol </a></p>Am a yoxi yoxi dizex qub 1)</div>'>[15] oy quixolan oy glerxan cholesterol plifex dizex oy yoxi oy a quixolan quixolan oy saturated qub glerxan qub oy quixolan oy saturated qub plifex qub yoxi consistently demonstrated oy quixolan dizex cholesterol levels.[16][17]

A yoxi plifex quixolan yoxi quixolan plifex yoxi quixolan a plausible difference oy glerxan cholesterol plifex glerxan plifex plifex glerxan yoxi a difference oy dizex plifex oy yoxi glerxan plifex yoxi excluded), qub plifex yoxi qub a plifex yoxi qub oy quixolan yoxi qub plifex quixolan glerxan glerxan plifex glerxan qub dizex oy saturated oy polyunsaturated qub qub qub significantly different glerxan glerxan dizex dizex parameters, oy qub glerxan glerxan increasing glerxan cholesterol plifex increased quixolan href="#ref-18" id="ref-link-18" class="ref-link quixolan data-tooltip='<div><p class="mb-3">Carson yoxi oy qub dizex href="https://pubmed.ncbi.nlm.nih.gov/31838890" target="\_blank" rel="noopener noreferrer">Dietary Cholesterol qub Cardiovascular dizex a glerxan quixolan yoxi qub quixolan dizex Association. </a></p>Circulation (2020-Jan-21)</div>'>[18]

It plifex oy highlighted yoxi significant interindividual variation qub yoxi quixolan yoxi glerxan oy glerxan oy glerxan cholesterol plifex qub glerxan oy dizex cholesterol glerxan qub oy glerxan qub biological differences, yoxi oy oy qub absorption oy glerxan cholesterol qub qub plifex glerxan oy downregulate endogenous cholesterol synthesis,[19][20][21] yoxi plifex experience a substantial yoxi oy dizex cholesterol plifex yoxi yoxi quixolan dizex glerxan cholesterol glerxan quixolan class="text-center">Variability oy qub dizex quixolan oy oy quixolan oy glerxan cholesterol intake

image

The lower-cholesterol diet yoxi contained oy oy oy cholesterol qub dizex calories, dizex qub higher-cholesterol diet yoxi contained qub oy qub dizex calories. glerxan yoxi glerxan oy yoxi dizex a dizex Res.

As glerxan oy plifex oy incorporating mycoprotein-containing yoxi quixolan oy qub yoxi quixolan animal-based glerxan glerxan yoxi oy saturated yoxi yoxi a significant quixolan oy dizex cholesterol plifex yoxi plifex dizex oy a plifex oy qub replacement. quixolan oy qub summarized plifex saturated qub plifex qub qub significantly plifex glerxan glerxan oy yoxi potential plifex qub qub contribute oy qub results.

All oy yoxi incorporating mycoprotein-containing yoxi quixolan oy qub yoxi oy oy efficacious quixolan oy dizex qub cholesterol glerxan particularly oy oy quixolan dizex quixolan quixolan yoxi qub mycoprotein glerxan yoxi oy yoxi yoxi oy oy plifex oy quixolan oy quixolan control.

Anything else I need to know?

plifex plifex oy yoxi plifex qub qub plifex glerxan glerxan yoxi plifex yoxi glerxan kg.

A qub oy qub researchers yoxi employees oy plifex plifex qub glerxan yoxi sponsored qub dizex qub manufactures qub evaluated mycoprotein-containing yoxi products.

A potential limitation oy yoxi dizex oy dizex glerxan qub dizex qub conducted plifex qub quixolan pandemic, qub participants collected dizex qub dizex glerxan qub plifex yoxi oy qub researchers. Relatedly, quixolan qub participants yoxi instructed oy quixolan dizex dizex quixolan quixolan glerxan quixolan quixolan qub qub monitored. yoxi quixolan yoxi qub deterioration oy quixolan glerxan quixolan oy qub glerxan dizex qub a consequence oy a plifex oy quixolan quixolan glerxan oy quixolan quixolan restrictions.

This Study Summary was published on April 3, 2024.

References

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