How to use Examine

Welcome to the new Examine!

For the past two years, we’ve been hard at work preparing a completely revamped website, dubbed Examine 2.0. It offers much-improved organization, usability, and content compared to the old site.

After literally thousands of hours of work revamping nearly every aspect of the site, Examine 2.0 launched on August 18th 2022. And we’re overjoyed to have you here using the new site!

If you have any questions or comments, please contact us here. Check out some answers to common questions below, which will help you get familiar with the new site and everything that’s changed. Enjoy!

–Kamal Patel, Co-founder of Examine

How is the Examine website organized?

Examine is organized unlike any health information site you’ve seen, so read these basics before digging in, if you can!



In scientific research, anything that’s tested in a trial is called an intervention. Fish oil, creatine, and low-carb diets are examples of interventions. Trials look at specific, measurable outcomes (such as LDL-C, skin elasticity, or self-rated anxiety) to see if an intervention “works”.

Examine covers 400+ health interventions and 700+ health outcomes. But people care about their health conditions and goals, not just specific outcomes. So we also have around 400 health conditions and goals pages.

The last (and broadest) part of the hierarchy is the health categories. On the upper left of any intervention or condition/goal page, you’ll see which of 25 health categories the page belongs to. The category pages are the backbone of Examine 2.0 — they collect all the related FAQs and study information in one place.

This is a lot to take in! So here’s a simple way to think about it: If you have a health condition or a health goal, you’re interested in what interventions might improve the outcomes related to this condition or goal. And since there are so many conditions and goals out there, we grouped them under 25 broad health categories to make the website easier to use.

How is Examine 2.0 different than the old Examine?

There are roughly one million ways the new site is better. Here are just three of them to wet your beak:

The site loads way faster

  • This came after a year of completely rewriting Examine's codebase from scratch, using the most modern development tools.

We're grading evidence now

  • The evidence for every single outcome is graded on a scale of A-F. And we're constantly working to improve these grades, so you get the most accurate assessment of any intervention-outcome relationship.

Everything is integrated together

  • We're no longer similar to other typical "blog" type health websites. Rather, we're possibly the only website with a strict hierarchy connecting together health conditions, outcomes, categories, and interventions.

How are individual Examine pages set up?

Most pages on Examine are split into two main parts: FAQs (the questions our readers want us to answer) and the Examine Database (the randomized trial data we systematically collect).

The first few FAQs on a page give you standardized information about the topic at hand. The specific type of information differs by page type.

So the first few condition page FAQs will let you know about signs and symptoms as well as common treatments, whereas those on intervention pages will tell you about potential benefits and harms of that intervention.

After those introductory FAQs, you’ll often see an Examine Database. It contains all the randomized trial data we’ve collected on the topic at hand. The purpose of the Examine Database is to provide a systematic and comprehensive source of data, so that you can see how a trial fits into the full body of research on a topic instead of just a few cherry-picked studies.

As a disclaimer of sorts, note that we’re always updating the trials in the Database. Examine has many hundreds of pages, and it takes some time to extract data from studies and add it to the Database. We also make errors at times, which we try to fix as soon as we find them or are notified!

Next, you may see a research feed that contains summaries of the newest studies, hot off the press. Finally, you’ll see even more FAQs on some pages. These FAQs provide more nitty gritty information, and we’ll be adding more and more of them to pages that don’t currently have many FAQs.

What’s free on Examine, and what do Examine+ members get?

We provide a ton of free information, but keep the lights on by selling memberships that provide readers with much more information, especially on the latest research.

Long ago, we decided not to clutter the site up with ads (how weird would it be if you saw ads for wasteful supplements right next to Examine data that showed a supplement didn’t work?). And since we didn’t want to accept money from supplement or food companies to hawk their products, our sole funding option is the Examine+ membership.

So what’s free and what’s paid? In short, all the FAQs are free, and some of the Examine Database is free. Everything else is paid. Examine+ members are able to unlock the full power of our research:

  • The evidence grades and data from thousands of studies in the Examine Database are fully unlocked for members. The grades are constantly being fine-tuned and reviewed, so that you can more accurately know what’s worth looking at and what’s junk.
  • The Research Feed is exclusive to members. You pick the health categories you’re interested in and get summaries of the most noteworthy of the latest studies. We add 150+ summaries each month, so you always know where the science currently stands on your particular interests.
  • 17 Supplement Guides, spanning around a thousand pages in total, tell you step-by-step which supplements are most and least promising for your particular health goals, along with how and when (and in what context) to take them.

Is Examine still useful if I’m not versed in science?

You might be intimidated by this huge, science-heavy website! We’re always trying to improve and revise our writing to make it more accessible by people without science backgrounds. But in the meantime, here are a couple things to note.

First, the first few FAQs on each page cover basic information that lays the groundwork for more detailed information further down in the page. If you understand these basic FAQs, you understand more than 95% of people out there!

Second, you can incrementally learn more about science and the research process, starting with our guide on How to Read Research. Given that there’s so much research produced each month and so many scientific disciplines, no single person understands everything. So you’re a learner just like all of us at Examine!

What method does Examine use to grade evidence?

We use an algorithm that incorporates the consistency of evidence (how often trials agree with each other about potential benefit) as well as the magnitude of effect (how large of a change was seen in trials).

We’re also starting to go back to individual studies to manually adjust grades up or down if needed. This is an ongoing process, given that we cover thousands of trials and just started offering grades in August of 2022. So expect some to change, although most will remain the same.

How do I ask Examine a question? How do I lavish Examine with praise? How do I critique Examine and tell them everything they’ve so obviously gotten wrong?

Contact us here.

Try to be gentle – we’re working hard to be as accurate and useful as possible, but we do err at times (as does everyone, right?). We don’t always have time for long back and forths about every single issue, but do welcome additional perspectives.

If you like the site, let us know! We love praise (as does everyone, right?).

And if you wish to know more: click here to explore Examine+.