HbA1c (Glycated hemoglobin) is a biomarker of glucose metabolism, and higher HbA1c is associated with more disease progression and comorbidities in states of insulin resistance or diabetes.

This page features 2 unique references to scientific papers.

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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what supplements affect HbA1c
Grade Level of Evidence
A Robust research conducted with repeated double blind clinical trials
B Multiple studies where at least two are double-blind and placebo controlled
C Single double blind study or multiple cohort studies
D Uncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific Consensus Comments
A Chromium
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
A Fish Oil
B Berberine
B Coenzyme Q10
B Magnesium
B Psyllium
B Conjugated Linoleic Acid
C Gynostemma pentaphyllum
C Spirulina
C Alpha-Lipoic Acid
C Citrullus colocynthis
C Olive leaf extract
C Panax ginseng
C Salacia reticulata
C Arginine
C Astaxanthin
C Benfotiamine
C Cocoa Extract
C Hesperidin
C Pycnogenol
C Red Clover Extract
C Rose Hip
C Royal Jelly
C Stevia
C Vitamin C
C Vitamin D
C Vitamin E
D Ruscus aculeatus
D Aronia melanocarpa
D Moringa oleifera
D Nigella sativa
D Safflower Oil
D Vanadium
D Yerba mate
D Blueberry
D Mangifera indica
D Salvia hispanica
D Sulbutiamine
D Tetradecyl Thioacetic Acid


  1. Evans SF1, et al Mango supplementation improves blood glucose in obese individuals . Nutr Metab Insights. (2014)
  2. Pardo-Andreu GL1, et al Mangifera indica L. (Vimang) protection against serum oxidative stress in elderly humans . Arch Med Res. (2006)

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