The ability to remember things currently being done (working memory) recently learned (short term) and possible for life (long term memory); some compounds enhance memory by reversing states of neural malaise (Fish Oil, Curcumin) whereas some can increase memory unilaterally (Bacopa monnieri).

This page features 14 unique references to scientific papers.

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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what supplements affect Memory
Grade Level of Evidence
A Robust research conducted with repeated double blind clinical trials
B Multiple studies where at least two are double-blind and placebo controlled
C Single double blind study or multiple cohort studies
D Uncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific Consensus Comments
A Ginkgo biloba
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
B Bacopa monnieri
B Melissa officinalis
B Caffeine
C PRL-8-53
C Blueberry
C CDP-choline
C Fish Oil
C Ginger
C Melatonin
C Modafinil
C Nicotine
C Nigella sativa
C Oxiracetam
C Phosphatidylserine
C Piracetam
C Red Clover Extract
C S-Adenosyl Methionine
C Vinpocetine
C Black Cohosh
C Choline
C Chromium
C Cocoa Extract
C Creatine
C Marijuana
C Polygala tenuifolia
C Sceletium tortuosum
C Vitamin E
D Pramiracetam
D Peppermint


  1. Buguet A, et al Modafinil, d-amphetamine and placebo during 64 hours of sustained mental work. II. Effects on two nights of recovery sleep . J Sleep Res. (1995)
  2. Biederman J, et al Efficacy and safety of modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder: results of a randomized, double-blind, placebo-controlled, flexible-dose study . Pediatrics. (2005)
  3. Kalechstein AD, De La Garza R 2nd, Newton TF Modafinil administration improves working memory in methamphetamine-dependent individuals who demonstrate baseline impairment . Am J Addict. (2010)
  4. Chapotot F, et al Distinctive effects of modafinil and d-amphetamine on the homeostatic and circadian modulation of the human waking EEG . Psychopharmacology (Berl). (2003)
  5. Pigeau R, et al Modafinil, d-amphetamine and placebo during 64 hours of sustained mental work. I. Effects on mood, fatigue, cognitive performance and body temperature . J Sleep Res. (1995)
  6. Baranski JV, Pigeau RA Self-monitoring cognitive performance during sleep deprivation: effects of modafinil, d-amphetamine and placebo . J Sleep Res. (1997)
  7. Schmaal L, et al Effects of modafinil on neural correlates of response inhibition in alcohol-dependent patients . Biol Psychiatry. (2013)
  8. Zack M, Poulos CX Effects of the atypical stimulant modafinil on a brief gambling episode in pathological gamblers with high vs. low impulsivity . J Psychopharmacol. (2009)
  9. Dean AC, et al Acute modafinil effects on attention and inhibitory control in methamphetamine-dependent humans . J Stud Alcohol Drugs. (2011)
  10. Turner DC, et al Cognitive enhancing effects of modafinil in healthy volunteers . Psychopharmacology (Berl). (2003)
  11. Bruce J, et al Impact of armodafinil on cognition in multiple sclerosis: a randomized, double-blind crossover pilot study . Cogn Behav Neurol. (2012)
  12. Müller U, et al Effects of modafinil on non-verbal cognition, task enjoyment and creative thinking in healthy volunteers . Neuropharmacology. (2013)
  13. Müller U, et al Effects of modafinil on working memory processes in humans . Psychopharmacology (Berl). (2004)
  14. Niepel G, et al Association of a deficit of arousal with fatigue in multiple sclerosis: effect of modafinil . Neuropharmacology. (2013)

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