Depression

Depression is a cognitive state associated with hopelessness and apathy. Clinical depression is a realm for medical doctors to address, but subclinical ennui might be counteracted with some supplements. Consider physical exercise as well, it might help a little.

   
The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Depression
GradeLevel of Evidence
ARobust research conducted with repeated double blind clinical trials
BMultiple studies where at least two are double-blind and placebo controlled
CSingle double blind study or multiple cohort studies
DUncontrolled or observational studies only
Level of Evidence
SupplementChange
Magnitude of Effect Size
Scientific ConsensusComments
AFish Oil
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
ASaffron
BZinc
BInositol
BChromium
CCreatine
CDehydroepiandrosterone
CPanax ginseng
CNicotine
CS-Adenosyl Methionine
CVitex agnus castus
CBacopa monnieri
CRhodiola Rosea
CL-Tyrosine
CGanoderma lucidum
CKava
CMaca
CVitamin C
CNefiracetam
CAshwagandha
CGinkgo biloba
CYamabushitake
CCentella asiatica
CN-Acetylcysteine
CRed Clover Extract
CMarijuana
DHoly Basil
DMagnesium
DLavender
DRoyal Jelly
DUridine
DVitamin B12
DPhenylpiracetam
DCurcumin
DAgmatine

References

  1. Keynan O, et al. Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial. Pain Med. (2010)

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