Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect depression
| Grade | Level of Evidence |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
| Multiple studies where at least two are double-blind and placebo controlled |
| Single double-blind study or multiple cohort studies |
| Uncontrolled or observational studies only |
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Level of Evidence ?
The amount of high quality evidence. The more evidence, the more we can trust the results.
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Outcome |
Magnitude of effect ?
The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results ?
Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
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Notes |
|---|---|---|---|---|
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Fish Oil |
All comparative evidence is now gathered in our Supplement Goals Reference. The evidence for each separate supplement is still freely available here. |
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Saffron | |||
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Zinc | |||
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Chromium | |||
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Inositol | |||
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Creatine | |||
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Red Clover Extract | |||
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Rhodiola Rosea | |||
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S-Adenosyl Methionine | |||
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Ashwagandha | |||
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Bacopa monnieri | |||
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Centella asiatica | |||
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Ganoderma lucidum | |||
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Kava | |||
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Maca | |||
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Panax ginseng | |||
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Vitex agnus castus | |||
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Yamabushitake | |||
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Dehydroepiandrosterone | |||
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Ginkgo biloba | |||
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L-Tyrosine | |||
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Marijuana | |||
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N-Acetylcysteine | |||
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Nefiracetam | |||
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Nicotine | |||
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Vitamin C | |||
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Agmatine | |||
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Curcumin | |||
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Holy Basil | |||
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Lavender | |||
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Magnesium | |||
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Phenylpiracetam | |||
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Royal Jelly | |||
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Uridine | |||
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Vitamin B12 | |||
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Vitamin D | |||