Scientific Information on Wrinkles
Wrinkles
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Summary of Wrinkles
Scientific Information on Wrinkles
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Human Effect Matrix
Unlocked for Examine membersThe Human Effect Matrix looks at human studies to tell you what supplements affect Wrinkles.
Full details on all Wrinkles supplements are available to Examine members.
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Supplement |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
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Notable
|
Very High See all 3 studies |
The appearance of fine (small) wrinkles appears to be reliably reduced with topical application of a nightly vitamin A cream, with efficacy in all ages assuming fine wrinkles are present.
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Minor
|
- See study |
Topical application of nicotinamide appears to slightly reduce the appearance of fine wrinkles (crow's feet).
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Minor
|
- See study |
There appears to be a slight decrease in skin wrinkling following topical application of 0.3% ginkgo for 28 days
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