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Urea

Urea is a metabolic byproduct of amino acid metabolism that is excreted by the kidneys.

Research analysis led by .
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Last Updated:

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Urea.

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Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor Very High See all 3 studies
An increase in urea is seen with citrulline supplementation (possibly due to increased serum ornithine sequestering ammonia)
grade-c Minor - See study
An increase in urea has been noted with glutamine supplementation
grade-c Minor Moderate See 2 studies
Mixed effects, but it appears that when ammonia is decreased that urea is also increased but if ammonia is unchanged whatever reason for this also means that urea is unchanged.

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