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Symptoms of Ulcerative Colitis

Ulcerative colitis (UC) is a subset of inflammatory bowel disease (the other being Crohn's Disease), and supplements that are thought to be preventative or therapeutic to UC are those that increase remission chance or prolong the time until symptoms arise.

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect symptoms of ulcerative colitis
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The mo re evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Andrographis paniculata Notable Very High See 2 studies
Appears to be quite effective based on preliminary evidence, with one study being comparable to sustained release mesalazine in potency.
grade-c Colostrum Notable - See study
One study using a solution of colostrum (as enema) in persons with distal colitis noted a large suppression of symptoms and inflammation relative to placebo. No studies available on oral supplementation of colostrum for inflammatory bowel diseases.
grade-c Curcumin Minor Very High See 2 studies
Symptoms of ulcerative colitis reduced with supplementation of curcumin
grade-d Psyllium Notable - See study
The potency of psyllium husk in controlling remission of ulcerative colitis is comparable to the reference drug mesalamine.
grade-d Vitamin E  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.