Symptoms of Systemic Lupus Erythematosus
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect symptoms of systemic lupus erythematosus
| Grade | Level of Evidence [show legend] |
|---|---|
|
Robust research conducted with repeated double-blind clinical trials |
|
Multiple studies where at least two are double-blind and placebo controlled |
|
Single double-blind study or multiple cohort studies |
|
Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
Notable
|
Very High See all 7 studies |
The decrease in symptoms of lupus as assessed by SLAM-R and BILAG at times reaches up to 50% symptom reduction and tends to exceed 30%, and the first pilot studies noted remission in all subjects (although they have not been replicated since). Oddly, benefit may come from lower doses (160mg EPA and 140mg DHA) with higher doses conferring less benefit
|
|
|
|
Minor
|
- See study |
Inflammatory symptoms associated with Lupus appear to be reduced with Vitamin D ingestion
|