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Symptoms of PMS

Premenopausal symptom (PMS) appears to be affected by a few supplements, with continual usage of these supplements able to reduce the symptoms of PMS including bloat and emotional instability.

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team.
Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect symptoms of pms
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The mo re evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Vitex agnus castus Strong Very High See all 7 studies
Vitex is the reference drug used for reductions in PMS symptoms, with about half of users experiencing a halving of menopausal symptoms with prolonged use (3+ cycles)
grade-c Saffron Notable - See study
One study assessing saffron on PMS symptoms noted that supplementation caused 76% of the participants to have more than a halving of overall symptoms (placebo reaching 8%), suggesting relatively potent effects.
grade-c Ginkgo biloba Minor Very High See 2 studies
There appear to be reductions in the symptoms of PMS associated with ginkgo supplementation, the degree of reduction being reported at up to 23.68%
grade-c Inositol Minor Moderate See 2 studies
Myo-inositol supplementation appears to be effective in reducing dysphoric and depressive symptoms during PMS
grade-c Krill Oil  
grade-c Valeriana officinalis  
grade-d Magnesium  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.