Quick Navigation

Symptoms of Parkinson's Disease

Parkinson's Disease is a form of dementia characterized by cell loss (usually dopamine producing cells) in a brain region called the substantia nigra, resulting in movement abnormalities. Some supplements may reduce movement and cognitive impairment of this state.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect symptoms of parkinson's disease
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Mucuna pruriens Notable Very High See all 3 studies
Possible symptoms reduction in Parkinson's Disease related to the L-DOPA content and theorized (but not proven) peripheral dopamine decarboxylase inhibitor; this is notable as a L-DOPA and carbidopa combination supplement is the reference for reducing parkinson's symptoms
grade-c Coenzyme Q10 Minor - See study
grade-c D-Serine Minor - See study
Preliminary evidence suggests that the standard dosage of D-Serine can alleviate some symptoms of Parkinson's disease

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.