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Symptoms of Irritable Bowel Syndrome

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team.
Published:
Last Updated:

Summary of Symptoms of Irritable Bowel Syndrome

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on Symptoms of Irritable Bowel Syndrome


Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect symptoms of irritable bowel syndrome
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The mo re evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-a Peppermint Notable Very High See all 8 studies
In persons with IBS, supplementation of peppermint oil appears to reliably and effectively reduce abdominal pain for as long as it is taken. Benefits are no longer seen two weeks after supplement cessation and abdominal pain is the only symptom notably reduced.
grade-d Pycnogenol Minor - See study
One open-label study (lacks blinding for investigators or subjects and no placebo-control) indicated that pynogenol efficacy for IBS symptoms was on par with some of the common pharmacological antispasmodic agents. Although the study design was weak, other studies demonstrating that pycnogenol has a relaxing effect on intestinal smooth muscle tissue lends some increased confidence that it may also be effective as a treatment for IBS.

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.