Quick Navigation

Symptoms of Intermittent Claudication

Intermittent claudication is a disorder of blood flow that limits mobility, and some supplements that aid in blood flow are known to prolong walking time and quality of life in persons with this condition.

Research analysis led by and reviewed by the Examine team.
Last Updated:

Easily stay on top of the latest nutrition research

Become an Examine Member to get access to the latest research. Get 150+ studies summarized for you across 25 different categories every month.

Members also have access to the Examine Study Database of 400+ supplements and their effects on 600+ health outcomes, as well as in-depth research analyses. Understand the whole body of nutrition and supplement evidence at a glance.

Get instant access — start your free 14-day trial

Already a Member? Click here to log in.


Human Effect Matrix

Unlocked for Examine Members

Easily stay on top of the latest nutrition research

Become an Examine Member to get access to the latest research. Get 150+ studies summarized for you across 25 different categories every month.

Members also have access to the Examine Study Database of 400+ supplements and their effects on 600+ health outcomes, as well as in-depth research analyses. Understand the whole body of nutrition and supplement evidence at a glance.

Get instant access — start your free 14-day trial

Already a Member? Click here to log in.


The Human Effect Matrix looks at human studies to tell you what supplements affect Symptoms of Intermittent Claudication.

Unlock the full Study Database with an Examine Membership. Get a 14-day free trial.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-a Minor Very High See all 6 studies
There appears to be reduced symptoms of intermittent claudication with ginkgo supplementation, although it seems to vary significantly from one individual to another and despite some persons experiencing large benefit the overall 'net' benefit is relatively minor.
grade-b Notable Very High See all 4 studies
Symptoms of intermittent claudation are notably reduced with L-Carnitine supplementation (the rate of improvement over time, as assessed by walking distance, seems to be doubled; ie. from 40% to 60% or 60% to 90%) and associated with the Propinyl-L-Carnitine form (found in the supplement GPLC). The role of propinoic acid cannot be ruled out at this time, and studies have not used basic L-carnitine or ALCAR
grade-c Notable - See study
The reduction of claudication symptoms appears to be fairly potent with ALA supplementation, although there is not a large body of evidence overall.

Become an Examine Member to view this information.

You can currently view 3 supplements as a non-member — becoming a Member will give you access to 5 total supplements on symptoms of intermittent claudication.

Already a Member? Log in now to access.

grade-c  
grade-c  

Stay on top of the latest research

To unlock the full archives of our Study Database and research analyses, become an Examine Member today.

Start your 14-day free trial