Quick Navigation

Symptoms of Intermittent Claudication

Intermittent claudication is a disorder of blood flow that limits mobility, and some supplements that aid in blood flow are known to prolong walking time and quality of life in persons with this condition.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

πŸ“ Don't waste your time on outdated information: Get Examine Personalized for access to the latest research on 400+ supplements and their effects on 600+ health outcomes.

Already a member? Click here to log in.

Human Effect Matrix

Unlocked for Examine members

The Human Effect Matrix looks at human studies to tell you what supplements affect Symptoms of Intermittent Claudication.

Full details on all Symptoms of Intermittent Claudication supplements are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-a Minor Very High See all 6 studies
There appears to be reduced symptoms of intermittent claudication with ginkgo supplementation, although it seems to vary significantly from one individual to another and despite some persons experiencing large benefit the overall 'net' benefit is relatively minor.
grade-b Notable Very High See all 3 studies
Symptoms of intermittent claudation are notably reduced with L-Carnitine supplementation (the rate of improvement over time, as assessed by walking distance, seems to be doubled; ie. from 40% to 60% or 60% to 90%) and associated with the Propinyl-L-Carnitine form (found in the supplement GPLC). The role of propinoic acid cannot be ruled out at this time, and studies have not used basic L-carnitine or ALCAR
grade-c Notable - See study
The reduction of claudication symptoms appears to be fairly potent with ALA supplementation, although there is not a large body of evidence overall.

Become an Examine member β€” free to try for 7 days β€” to view this information.

You can currently view 3 supplements as a non-member - becoming a member will give you access to 5 total supplements on symptoms of intermittent claudication.

Already a member? Log in now to access.

grade-c  
grade-c  

Become an Examine Personalized member to access the latest nutrition research on over 400 supplements across more than 600 different health goals, outcomes, conditions, and more.

Becoming an Examine subscriber unlocks the Human Effect Matrix for supplements, as well as all health topics on Examine.com. We summarize all the latest research so that you can make the best decisions for your health based on accurate and not up-to-date information.

Plus, you get a monthly summary of the latest research on the health topics you care about.