Quick Navigation

Symptoms of Fibromyalgia

Fibromyalgia is a nonspecific pain disorder with currently unknown causes, although supplements are still being investigated for the purpose of reducing this pain.

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect symptoms of fibromyalgia
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The mo re evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Coenzyme Q10 Strong Very High See all 5 studies
CoQ10 appears to be quite strongly effective for reducing symptoms of fibromyalgia (strong rating may be retracted at a later time when other reference drugs arise)
grade-c L-Carnitine Minor - See study
Fibromyalgic symptoms are reduced with carnitine ingestion
grade-c S-Adenosyl Methionine Minor - See study
A decrease in soreness symptoms of fibromyalgia (with no apparent effect on force production) has been noted with SAMe supplementation.
grade-d Chlorella Minor - See study
May have efficacy in reducing pain associated with fibromyalgia, but requires more evidence
grade-d D-Ribose  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.