The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect symptoms of diabetic neuropathy.
| Grade | Level of Evidence [show legend] |
|---|---|
|
Robust research conducted with repeated double-blind clinical trials |
|
Multiple studies where at least two are double-blind and placebo controlled |
|
Single double-blind study or multiple cohort studies |
|
Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Supplement |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
Notable
|
Very High See 2 studies |
Not yet compared to reference drugs, but it has been subject to a meta-analysis and appears to be more effective than other options for reducing nerve pain associated with diabetes. The lack of a reference comparison and some evidence suggesting no effect prevent a strong rating.
|
|
|
|
Minor
|
- See study |
A reduction in symptoms associated with diabetic neuropathy has been noted with magnesium supplementation
|
|
|
|
Minor
|
- See study |
One study noted a small reduction in symptoms, Much more evidence is needed.
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|
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