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Subjective Well-Being

Self-reported ratings of well being and happiness; either in general (euphoria-inducing compound) or reducing a disease state to enough of a degree to make the persons relatively happy.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect subjective well-being
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Notable Very High See all 4 studies
The increase in well being appears to be quite large, but secondary to reducing anxiety. At least one study has noted that, in healthy persons subject to a minor stressor (testing) that kava enhanced cheerfulness
grade-b Notable Very High See all 4 studies
Increases in subjective well being and contentment in fatigued or stressed individuals appears to be greater than other supplements.
grade-b Minor Moderate See all 11 studies
The influence of creatine on well being and general happiness is usually dependent on it treating a disease state; there does not appear to be a per se benefit to well being.
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All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.