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Individuals with small intestinal bacterial overgrowth (SIBO) have higher concentrations of bacteria relative to people without the disorder.

Our evidence-based analysis on sibo features 14 unique references to scientific papers.

Research analysis led by and reviewed by the Examine team.
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  1. ^ Sherwood L. Gorbach.. Medical Microbiology. 4th edition. Chapter 95Microbiology of the Gastrointestinal Tract.
  2. ^ Francisco Guarner, Juan-R Malagelada. Gut flora in health and disease. Lancet. (2003)
  3. ^ den Besten G, et al. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res. (2013)
  4. ^ June L Round, Sarkis K Mazmanian. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol. (2009)
  5. ^ a b Jan Bures, et al. Small intestinal bacterial overgrowth syndrome. World J Gastroenterol. (2010)
  6. ^ P P Toskes, et al. Small intestinal mucosal injury in the experimental blind loop syndrome. Light- and electron-microscopic and histochemical studies. Gastroenterology. (1975)
  7. ^ Shweta Kapil, et al. Small intestinal bacterial overgrowth and toll-like receptor signaling in patients with non-alcoholic fatty liver disease. J Gastroenterol Hepatol. (2016)
  8. ^ Savio C Reddymasu, Sandra Sostarich, Richard W McCallum. Small intestinal bacterial overgrowth in irritable bowel syndrome: are there any predictors?. BMC Gastroenterol. (2010)
  9. ^ Longstreth GF, et al. Functional bowel disorders. Gastroenterology. (2006)
  10. ^ P Kerlin, L Wong. Breath hydrogen testing in bacterial overgrowth of the small intestine. Gastroenterology. (1988)
  11. ^ I Hamilton, et al. Simultaneous culture of saliva and jejunal aspirate in the investigation of small bowel bacterial overgrowth. Gut. (1982)
  12. ^ Mohamed Othman, Roberto Agüero, Henry C Lin. Alterations in intestinal microbial flora and human disease. Curr Opin Gastroenterol. (2008)
  13. ^ Eamonn M M Quigley, Rodrigo Quera. Small intestinal bacterial overgrowth: roles of antibiotics, prebiotics, and probiotics. Gastroenterology. (2006)
  14. ^ Wai-Kit Lo, Walter W Chan. Proton pump inhibitor use and the risk of small intestinal bacterial overgrowth: a meta-analysis. Clin Gastroenterol Hepatol. (2013)