Also Known As
Sex Hormone Binding Globulin (SHBG) is a globulin that is able to bind to and sequester steroid hormones such as estrogen, testosterone, and DHT. Its elevations are associated with less activity of the steroid hormones.
Follow this Page for updates
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect sex hormone binding globulin
|Grade||Level of Evidence|
|Robust research conducted with repeated double-blind clinical trials|
|Multiple studies where at least two are double-blind and placebo controlled|
|Single double-blind study or multiple cohort studies|
|Uncontrolled or observational studies only|
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
All comparative evidence is now gathered in our A-to-Z Supplement Reference.
The evidence for each separate supplement is still freely available here.
|Red Clover Extract|
|Eurycoma Longifolia Jack|
"Sex Hormone Binding Globulin," Examine.com, published on 5 July 2013, last updated on 29 April 2017, https://examine.com/topics/sex-hormone-binding-globulin/