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Serum Folate

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Summary of Serum Folate

Scientific Information on Serum Folate

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Serum Folate.

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Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b - Very High See all 4 studies
Chronically there are no changes to serum folate due to the body normalizing folate levels, but acute supplementation can reduce folate concentrations in serum sharply for a short time.
grade-c - - See study
There do not appear to be any significant changes to circulating folate seen with supplementation of red clover extract.
grade-c - - See study
Serum folate does not appear to be modified with supplementation of vitamin E.

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