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Serum DHEA

Serum DHEA refers to the concentration of DHEA in the blood, a steroid hormone precursor. Increasing DHEA concentrations is thought to reduce some side-effects of aging and promote longevity.

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Things To Know & Note

Also Known As

DHEA, dehydroepiandrosterone

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect serum dhea
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The mo re evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-a Dehydroepiandrosterone Strong Very High See all 13 studies
Supplemental DHEA results in a reliable and significant increase in DHEA concentrations in the blood (both sulfated DHEAS and unsulfated DHEA)
grade-c Ashwagandha Minor - See study
A slight increase has been detected in serum DHEA sulfate (13.2%) with 60 days of ashwagandha supplementation.
grade-c Chromium - - See study
Chromium supplementation does not appear to alter serum concentrations of DHEA or sulfated DHEA.
grade-c Eurycoma Longifolia Jack - - See study
No significant changes in the sulfate form of DHEA (DHEA-S) is noted after twelve continual weeks of supplementation
grade-d Zinc  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.