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Sedation

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Summary of Sedation

Scientific Information on Sedation

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Sedation.

Full details on all Sedation supplements are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Strong Very High See 2 studies
Modafinil (300mg) taken prior to sleep is as potent as 20mg D-amphetamine in reducing the need to sleep and improving cognitive performance during intentional sleep deprivation. Occasionally, this potency manifests itself as the 'side-effect' of insomnia in some persons who take it in the AM
grade-c Minor - See study
An increase in sedation has been noted with aromatherapy, but not with oral usage of lavender supplements
grade-c Minor Very High See 2 studies
Doses above 750mg may be associated with the 'morning hangover' side effect (sleepiness upon waking) whereas lower doses of 400mg have not been associated with such.

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