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Protein Carbonyl Content

Similar to how lipid peroxidation measures oxidation as it applies to lipids, protein carbonyls measure the oxidation rates of protein structures. The accumulation of protein carbonyls is highly associated with cellular aging.

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect protein carbonyl content
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The mo re evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Alpha-Lipoic Acid Minor - See study
Appears to reduce protein carbonylation, which may be related to the antioxidative effects
grade-c Eleutherococcus senticosus Minor - See study
A decrease in protein carbonylation has been noted, which is thought to be secondary to antioxidative effects
grade-c Methylsulfonylmethane Minor - See study
A decrease in protein carbonylation is noted with MSM supplementation
grade-c Curcumin - - See study
No significant influence on protein carbonylation has been noted with curcumin ingestion

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.