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Progesterone

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Summary of Progesterone

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on Progesterone

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect progesterone.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c - Very High See 2 studies
Mixed effects on progesterone (and 17-hydroxyprogesterone) leaning towards no significant influence (although increases have been noted)
grade-d - - See study
No effect on progesterone in women with PCOS.
grade-d - Moderate See all 4 studies
Mixed evidence, with some studies suggesting an increase for postmenopausal women, but the overall evidence not pointing to a consistent or reliable effect.