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Postpartum Depression

Postpartum depression is a transient depressive state that occurs after the birth of a child, and is a target for anti-depressive compounds that have been confirmed to be safe to both mother and child.

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect postpartum depression
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Fish Oil - Very High See all 5 studies
There does not appear to be any unique effect of supplemental fish oil on postpartum depression. Fish oil in postpartum and perinatal periods follows the same motifs as other depressive states, with EPA being the active molecule but likely only of benefit in major depressive disorder

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.