Plasma Glutamine Research Analysis

Summary of Plasma Glutamine

Scientific Information on Plasma Glutamine

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect plasma glutamine

Grade	Level of Evidence [show legend]
	Robust research conducted with repeated double-blind clinical trials
	Multiple studies where at least two are double-blind and placebo controlled
	Single double-blind study or multiple cohort studies
	Uncontrolled or observational studies only

Level of Evidence ? The amount of high quality evidence. The mo re evidence, the more we can trust the results.	Outcome	Magnitude of effect ? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.	Consistency of research results ? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.	Notes
	Alanylglutamine	Minor	Very High See 2 studies	Higher doses (0.09-0.2g/kg) of oral alanylglutamine appear to increase plasma glutamine, and when compared to glutamine itself this dipeptide is more bioavailable
	Citrulline	Minor	Moderate See 2 studies	Although acute usage does not appear to influence plasma glutamine, a week of high dose supplementation (0.18g/kg) has been noted to reduce glutamine concentrations slightly.

All comparative evidence is now gathered in our A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available here.