Quick Navigation

Oxygenation Cost of Exercise

The oxygenation cost of exercise refers to how much oxygen is required to metabolize energy efficiently, and a reduction in this cost signifies more efficiency and improved physical performance. Improved oxygen efficiency tends to result from increasing nitric oxide.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Easily stay on top of nutrition research

Become an Examine.com member to get access to the latest research. 150+ studies summarized across 25 different categories every month.

Becoming a member also unlocks our study database of 400+ supplements and their effects on 600+ health outcomes.

Already a member? Click here to log in.

Make informed decisions about your health

Human Effect Matrix

Unlocked for Examine members

The Human Effect Matrix looks at human studies to tell you what supplements affect Oxygenation Cost of Exercise.

Full details on all Oxygenation Cost of Exercise supplements are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Notable Very High See 2 studies
A notable reduction in the oxygenation cost of exercise associated with nitrate supplementation.
grade-c Minor Moderate See 2 studies
When nitric oxide is increased, the oxygenation cost of exercise appears to be decreased. This is unreliable with supplemental L-arginine as arginine is unreliable in increasing nitric oxide
grade-c Minor - See study
Effective, but to a small degree based on one trial.
Become an Examine member — free to try for 14 days — to view this information.



You can currently view 3 supplements as a non-member - becoming a member will give you access to 7 total supplements on oxygenation cost of exercise.

Already a member? Log in now to access.

grade-c  
grade-c  
grade-c  
grade-d  

Stay on top of the latest research

Become an Examine Personalized member to access the latest nutrition research on over 400 supplements across more than 600 different health goals, outcomes, conditions, and more. Information tailored to you, updated every month.

Bonus: unlock the supplement Human Effect Matrix and all health topics on Examine.com.