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Noradrenaline

Noradrenaline is a catecholamine involved in the flight or fight response, and has a fairly important role as a neurotransmitter in the body. Elevations of serum noradrenline are thought to reflect increases in cerebral noradrenaline.

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Things To Know & Note

Also Known As

norepinephrine

Caution Notice

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect noradrenaline
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Melatonin Minor High See all 4 studies
A decrease in noradrenaline appears to reliably occur after melatonin ingestion, but only at rest; this reduction is abolished upon moving
grade-b Cocoa Extract - Very High See all 3 studies
Peripheral concentrations of noradrenaline do not appear to be influenced by supplementation of cocoa.
grade-c Mucuna pruriens Minor - See study
The reduction in noradrenaline levels seen in infertility is normalized following mucuna ingestion
grade-c Sodium Bicarbonate  
grade-c Branched Chain Amino Acids  
grade-c Creatine  
grade-c L-Tyrosine  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.

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