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Non-celiac gluten sensitivity

Non-celiac gluten sensitivity (NCGS) refers to a possible condition in subset of people (often self-diagnosed) who report problems when consuming gluten but don’t have any detectable autoimmune or allergic response in their bodies.

Research analysis led by and reviewed by the Examine team.
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Summary of Non-celiac gluten sensitivity

Non-celiac gluten sensitivity (NCGS) is a poorly-defined condition that has been observed since the 1980s. It refers to a possible condition in subset of people (often self-diagnosed) who report problems when consuming gluten but don’t have any detectable autoimmune or allergic response in their bodies. NCGS is currently a diagnosis of exclusion. That means it is diagnosed when an individual has had both allergic and autoimmune mechanisms ruled out, and the problems they experienced when eating gluten-containing products go away on a gluten-free diet (GFD). This would ideally in a blinded fashion to avoid any placebo effect of the dietary intervention.

Things to Note

Also Known As

NCGS, Non-celiac wheat sensitivity, Non-coeliac gluten sensitivity