Myostatin

Last Updated: May 7, 2020

A stop lever on muscle protein synthesis with no other known roles in the body, abolishing Myostatin in the body results in excessive muscle growth and a reduction of fat mass; the 'holy grail' of bodybuilding due to its potency, supplements targeting Myostatin are lacklustre.

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References
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  2. ^Lebrasseur NKBuilding muscle, browning fat and preventing obesity by inhibiting myostatinDiabetologia.(2012 Jan)
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  14. ^Double muscling in cattle due to mutations in the myostatin gene
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  20. ^Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates
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  39. ^Lee SJQuadrupling muscle mass in mice by targeting TGF-beta signaling pathwaysPLoS One.(2007 Aug 29)
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  52. ^Willoughby DSEffects of heavy resistance training on myostatin mRNA and protein expressionMed Sci Sports Exerc.(2004 Apr)
  53. ^Kim JS, Petrella JK, Cross JM, Bamman MMLoad-mediated downregulation of myostatin mRNA is not sufficient to promote myofiber hypertrophy in humans: a cluster analysisJ Appl Physiol.(2007 Nov)
  54. ^Heinemeier KMUsing ribosomal RNA as a reference in mRNA quantificationJ Appl Physiol.(2007 Nov)
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  62. ^Metabolic characteristics and body composition in house finches: effects of seasonal acclimatization
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Examine Database References
  1. Spirulina - Reza Bagheri, Raoof Negaresh, Mohamad S Motevalli, Alexei Wong, Damoon Ashtary-Larky, Mehdi Kargarfard, Amir RashidlamirSpirulina supplementation during gradual weight loss in competitive wrestlersBr J Nutr.(2021 Mar 15)
  2. Creatine - Saremi A, Gharakhanloo R, Sharghi S, Gharaati MR, Larijani B, Omidfar KEffects of oral creatine and resistance training on serum myostatin and GASP-1Mol Cell Endocrinol.(2010 Apr 12)