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Muscle Soreness

Muscle soreness refers to the percieved soreness or tender state of muscle tissue following physical exercise, usually manifesting after a short delay (and hence its common name of 'delayed onset muscle soreness' or DOMS).

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Muscle Soreness.

Full details on all Muscle Soreness supplements are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b - High See all 3 studies
Although one study suggests a decrease, most evidence suggest no significant influence
grade-c Minor - See 2 studies
It is possible bromelain might reduce muscle soreness, but currently the evidence does not support this claim (although the trial to note a failure of bromelain also noted a failure with Ibuprofen, a known active drug)
grade-c Minor Very High See all 3 studies
Some studies have found a reduction when taking citrulline acutely prior to exercise, though this isn't entirely consistent and much more research is needed to confirm its effects.

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Things to Note

Also Known As

Delayed onset muscle soreness, DOMS