Migraine
Introducing Evidence-based Keto: Your no-hype guide to the ketogenic diet
We've spent the past year analyzing the research on the keto diet, and have just released Evidence-based Keto.
Clocking in at over 200 pages with 500+ references, it's the unbiased guide you need to the ketogenic diet.
ON SALE THIS WEEK: Evidence-based Keto
Unbiased truth on keto and long-term effects on health, safety, pre-existing conditions, losing weight, and more.
Frequently Asked Questions about Migraine
Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect migraine
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
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The amount of high quality evidence. The more
evidence, the more we can trust the results.
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Outcome |
Magnitude of effect
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The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results
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Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
|---|---|---|---|---|
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Strong
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Very High See all 5 studies |
Feverfew appears to be strongly effective in reducing migraines when the population in question are people with high frequency migraines possibly accompanied by auras. Feverfew is not as effective, although still somewhat effective, in persons with less frequent migraines.
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Notable
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Moderate See all 7 studies |
Riboflavin supplementation appears to be quite effective in reducing migraine frequency based on preliminary research. The effect of riboflavin on intensity is still undetermined, and the optimal dose is not known as while most studies use 400mg one found similar benefits with 25mg.
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Notable
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- See study |
Seems to reduce symptoms of migraines a bit more than other PMS related symptoms, but for the most part the reduction seen in migraines is solely a reduction of PMS symptoms.
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Everything you need to know about the keto diet
When we asked our users what they wanted us to cover, many of them mentioned the keto diet.
So we listened. We spent the year looking up the research on the ketogenic diet to help guide you in your journey.
With Evidence-based Keto, Examine.com gives you all the scientific research, but in understandable language with tons of informative infographics. No opinion, no bias, no conflict of interest.
If you’re interested in keto, this is a must-have unbiased source.
References
- Evaluation of Consumer Complaints Related to Aspartame Use.
- Maher TJ, Wurtman RJ. Possible neurologic effects of aspartame, a widely used food additive. Environ Health Perspect. (1987)
- Kühn R, Graner H, Soukup P. {Experiences in the expert evaluation of nucleus pulposus prolapse}. Beitr Orthop Traumatol. (1975)
- Aspartame ingestion and headaches.
- Levy PS, Hedeker D, Sanders PG. Aspartame and headache. Neurology. (1995)
- Roberts HJ. Aspartame and headache. Neurology. (1995)
- Schiffman S. Aspartame and headache. Neurology. (1995)
- Newman LC, Lipton RB. Migraine MLT-down: an unusual presentation of migraine in patients with aspartame-triggered headaches. Headache. (2001)
- Pisarik P, Kai D. Vestibulocochlear toxicity in a pair of siblings 15 years apart secondary to aspartame: two case reports. Cases J. (2009)